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Literature summary extracted from

  • Clapham, J.C.; Wilderspin, A.
    Purification and kinetic properties of cardiac calmodulin dependent cyclic nucleotide PDE (PDE-I) (1996), Biochem. Soc. Trans., 24, 320-321.
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.4.17 8-methoxymethyl(-3-isobutyl-1-)methylxanthine
-
 Canis lupus familiaris
3.1.4.17 vinpocetine
-
 Canis lupus familiaris
3.1.4.17 zaprinast
-
 Canis lupus familiaris

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.1.4.17 Ca2+ Ca2+/calmodulin dependent Canis lupus familiaris

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.1.4.17 68000
-
 2 * 68000, SDS-PAGE Canis lupus familiaris
3.1.4.17 150000
-
 gel filtration Canis lupus familiaris

Organism

EC Number Organism UniProt Comment Textmining
3.1.4.17 Canis lupus familiaris
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.1.4.17
-
 Canis lupus familiaris

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.4.17 heart
-
 Canis lupus familiaris
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.4.17 3',5'-cAMP + H2O
-
 Canis lupus familiaris 5'-AMP
-
 ?
3.1.4.17 3',5'-cGMP + H2O
-
 Canis lupus familiaris 5'-GMP
-
 ?
3.1.4.17 nucleoside 3',5'-cyclic phosphate + H2O
-
 Canis lupus familiaris nucleoside 5'-phosphate
-
 ?

Subunits

EC Number Subunits Comment Organism
3.1.4.17 dimer 2 * 68000, SDS-PAGE Canis lupus familiaris