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Literature summary extracted from
- Interconversion of apo- and holofatty acid synthetases of rat and pigeon liver (1979), Methods Enzymol., 62, 249-262.
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.1.4.14 | Mg2+ | required, or other divalent cations | Rattus norvegicus |  |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.1.4.14 | acyl-carrier protein + H2O | Rattus norvegicus | CoA donates 4'-phosphopantetheine as prosthetic group | 4'-phosphopantetheine + apoprotein | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.1.4.14 | Rattus norvegicus | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 3.1.4.14 | partial | Rattus norvegicus |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.1.4.14 | liver | - |
Rattus norvegicus | - |
Storage Stability
| EC Number | Storage Stability | Organism |
|---|---|---|
| 3.1.4.14 | -20oC, dithiothreitol, several months, no loss of activity | Rattus norvegicus |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.1.4.14 | acyl-carrier protein + H2O | CoA donates 4'-phosphopantetheine as prosthetic group | Rattus norvegicus | 4'-phosphopantetheine + apoprotein | - |
? | |
| 3.1.4.14 | holo-fatty acid synthetase + H2O | specific for rat liver holo-fatty acid synthetase, no activity on pigeon liver holo-fatty acid synthetase | Rattus norvegicus | apo-fatty acid synthetase + 4'-phosphopantetheine | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 3.1.4.14 | holofatty acid synthetase hydrolase | - |
Rattus norvegicus |
Temperature Optimum [°C]
| EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 3.1.4.14 | 37 | - |
- |
Rattus norvegicus |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 3.1.4.14 | 7 | - |
- |
Rattus norvegicus |
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Release 2023.1 (January 2023)
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