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Literature summary extracted from

  • Taylor, G.S.; Ladd, A.; James, J.; Greene, B.; English, D.
    Characterization of phosphatidic acid phosphohydrolase in neutrophil subcellular fractions (1993), Biochim. Biophys. Acta, 1175, 219-224.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.1.3.4 Triton X-100 plasma membrane-associated activity is absolutely dependent on detergent Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.3.4 F-
-
 Homo sapiens
3.1.3.4 NEM inhibition of cytosolic and light membrane activity Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.1.3.4 0.062
-
 phosphatidic acid
-
 Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.1.3.4 cytosol 20% of the activity Homo sapiens 5829
-
3.1.3.4 additional information the majority of the activity is localized in particulate fraction Homo sapiens
-
-
3.1.3.4 plasma membrane
-
 Homo sapiens 5886
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.1.3.4 Ca2+ moderate inhibition of cytosolic and particulate activity Homo sapiens
3.1.3.4 Mg2+ markedly potentiates the cytosolic but not the particulate activity Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
3.1.3.4 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.3.4 neutrophil
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.3.4 phosphatidic acid + H2O
-
 Homo sapiens 1,2-diacyl-sn-glycerol + phosphate
-
 ?