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Literature summary extracted from

  • Walker, J.B.
    Streptomycin-6-P phosphohydrolase (1975), Methods Enzymol., 43, 465-470.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.3.39 amino alcohols
-
 Streptomyces bikiniensis
3.1.3.39 amino alcohols
-
 Streptomyces galbus
3.1.3.39 amino alcohols
-
 Streptomyces griseocarneus
3.1.3.39 amino alcohols
-
 Streptomyces griseus
3.1.3.39 EDTA
-
 Streptomyces bikiniensis
3.1.3.39 EDTA
-
 Streptomyces galbus
3.1.3.39 EDTA
-
 Streptomyces griseocarneus
3.1.3.39 EDTA
-
 Streptomyces griseus
3.1.3.39 phosphate
-
 Streptomyces bikiniensis
3.1.3.39 phosphate
-
 Streptomyces galbus
3.1.3.39 phosphate
-
 Streptomyces griseocarneus
3.1.3.39 phosphate
-
 Streptomyces griseus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.3.39 dihydrostreptomycin 6-phosphate + H2O Streptomyces bikiniensis final step in streptomycin biosynthesis dihydrostreptomycin + phosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.3.39 Streptomyces bikiniensis
-
 ATCC 11062
-
3.1.3.39 Streptomyces galbus
-
 ATCC 14077
-
3.1.3.39 Streptomyces griseocarneus
-
 ATCC 12628
-
3.1.3.39 Streptomyces griseus
-
 ATCC 12475
-
3.1.3.39 Streptomyces griseus
-
 little or no activity in ATCC 10971
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.3.39 mycelium
-
 Streptomyces griseus
-
3.1.3.39 mycelium
-
 Streptomyces bikiniensis
-
3.1.3.39 mycelium
-
 Streptomyces griseocarneus
-
3.1.3.39 mycelium
-
 Streptomyces galbus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.3.39 dihydrostreptomycin 6-phosphate
-
 Streptomyces griseus dihydrostreptomycin + phosphate
-
 ?
3.1.3.39 dihydrostreptomycin 6-phosphate
-
 Streptomyces bikiniensis dihydrostreptomycin + phosphate
-
 ?
3.1.3.39 dihydrostreptomycin 6-phosphate
-
 Streptomyces griseocarneus dihydrostreptomycin + phosphate
-
 ?
3.1.3.39 dihydrostreptomycin 6-phosphate
-
 Streptomyces galbus dihydrostreptomycin + phosphate
-
 ?
3.1.3.39 dihydrostreptomycin 6-phosphate + H2O final step in streptomycin biosynthesis Streptomyces bikiniensis dihydrostreptomycin + phosphate
-
 ?
3.1.3.39 ethanolamine phosphate + H2O
-
 Streptomyces griseus ?
-
 ?
3.1.3.39 ethanolamine phosphate + H2O
-
 Streptomyces bikiniensis ?
-
 ?
3.1.3.39 ethanolamine phosphate + H2O
-
 Streptomyces griseocarneus ?
-
 ?
3.1.3.39 ethanolamine phosphate + H2O
-
 Streptomyces galbus ?
-
 ?
3.1.3.39 p-nitrophenyl phosphate + H2O
-
 Streptomyces griseus p-nitrophenol + phosphate
-
 ?
3.1.3.39 p-nitrophenyl phosphate + H2O
-
 Streptomyces bikiniensis p-nitrophenol + phosphate
-
 ?
3.1.3.39 p-nitrophenyl phosphate + H2O
-
 Streptomyces griseocarneus p-nitrophenol + phosphate
-
 ?
3.1.3.39 p-nitrophenyl phosphate + H2O
-
 Streptomyces galbus p-nitrophenol + phosphate
-
 ?
3.1.3.39 streptidine 6-phosphate + H2O
-
 Streptomyces griseus dihydrostreptomycin + phosphate
-
 ?
3.1.3.39 streptidine 6-phosphate + H2O
-
 Streptomyces bikiniensis dihydrostreptomycin + phosphate
-
 ?
3.1.3.39 streptidine 6-phosphate + H2O
-
 Streptomyces griseocarneus dihydrostreptomycin + phosphate
-
 ?
3.1.3.39 streptidine 6-phosphate + H2O
-
 Streptomyces galbus dihydrostreptomycin + phosphate
-
 ?
3.1.3.39 streptomycin 6-phosphate + H2O
-
 Streptomyces griseus streptomycin + phosphate
-
 ?
3.1.3.39 streptomycin 6-phosphate + H2O
-
 Streptomyces bikiniensis streptomycin + phosphate
-
 ?
3.1.3.39 streptomycin 6-phosphate + H2O
-
 Streptomyces griseocarneus streptomycin + phosphate
-
 ?
3.1.3.39 streptomycin 6-phosphate + H2O
-
 Streptomyces galbus streptomycin + phosphate
-
 ?
3.1.3.39 streptomycin-3''-phosphate + H2O
-
 Streptomyces griseus streptomycin + phosphate
-
 ?
3.1.3.39 streptomycin-3''-phosphate + H2O
-
 Streptomyces bikiniensis streptomycin + phosphate
-
 ?
3.1.3.39 streptomycin-3''-phosphate + H2O
-
 Streptomyces griseocarneus streptomycin + phosphate
-
 ?
3.1.3.39 streptomycin-3''-phosphate + H2O
-
 Streptomyces galbus streptomycin + phosphate
-
 ?
3.1.3.39 Tris-phosphate + H2O
-
 Streptomyces griseus ?
-
 ?
3.1.3.39 Tris-phosphate + H2O
-
 Streptomyces bikiniensis ?
-
 ?
3.1.3.39 Tris-phosphate + H2O
-
 Streptomyces griseocarneus ?
-
 ?
3.1.3.39 Tris-phosphate + H2O
-
 Streptomyces galbus ?
-
 ?