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Literature summary extracted from

  • Londesborough, J.; Vuorio, O.
    Trehalose-6-phosphate synthase/phosphatase complex from bakers' yeast: purification of a proteolytically activated form (1991), J. Gen. Microbiol., 137, 323-330.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.4.1.15 TPS-activator protein activation Saccharomyces cerevisiae
3.1.3.12 phosphate increases activity Saccharomyces cerevisiae

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.4.1.15 ADPglucose
-
Saccharomyces cerevisiae
2.4.1.15 phosphate
-
Saccharomyces cerevisiae
2.4.1.15 UDPglucuronate
-
Saccharomyces cerevisiae

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.4.1.15 Mg2+ optimal concentration is 1-2 mM Saccharomyces cerevisiae

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.4.1.15 57000
-
x * 115000 + x * 57000, complex of EC 2.4.1.15/EC 3.1.3.12, SDS-PAGE Saccharomyces cerevisiae
2.4.1.15 115000
-
x * 115000 + x * 57000, complex of EC 2.4.1.15/EC 3.1.3.12, SDS-PAGE Saccharomyces cerevisiae
2.4.1.15 300000
-
complex of EC 2.4.1.15/EC 3.1.3.12, gel filtration Saccharomyces cerevisiae

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.15 Saccharomyces cerevisiae
-
-
-
3.1.3.12 Saccharomyces cerevisiae
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.4.1.15 trehalose-6-phosphate synthase/phosphatase complex, EC 2.4.1.15/EC 3.1.3.12 Saccharomyces cerevisiae
3.1.3.12 trehalose-6-phosphate synthase/phosphatase complex Saccharomyces cerevisiae

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.4.1.15 15
-
-
Saccharomyces cerevisiae
3.1.3.12 additional information
-
-
Saccharomyces cerevisiae

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.15 UDPglucose + glucose 6-phosphate
-
Saccharomyces cerevisiae trehalose 6-phosphate + UDP
-
?
3.1.3.12 trehalose-6-phosphate + H2O
-
Saccharomyces cerevisiae trehalose + phosphate
-
?

Subunits

EC Number Subunits Comment Organism
2.4.1.15 oligomer x * 115000 + x * 57000, complex of EC 2.4.1.15/EC 3.1.3.12, SDS-PAGE Saccharomyces cerevisiae

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
2.4.1.15 5
-
phosphate
-
Saccharomyces cerevisiae