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Literature summary extracted from
- Purification and characterization of mouse liver glyoxalase II (1980), Biochim. Biophys. Acta, 611, 168-173.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.1.2.6 | glutathione | - |
Mus musculus |  |
| 3.1.2.6 | methylglyoxal | - |
Mus musculus | |
| 3.1.2.6 | methylglyoxal-glutathione hemimercaptal | - |
Mus musculus | |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 3.1.2.6 | 0.27 | - |
S-D-lactoylglutathione | - |
Mus musculus | |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 3.1.2.6 | 29500 | - |
1 * 29500, SDS-PAGE | Mus musculus |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.1.2.6 | Mus musculus | - |
Swiss mouse | - |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 3.1.2.6 | - |
Mus musculus |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.1.2.6 | liver | - |
Mus musculus | - |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 3.1.2.6 | 614.7 | - |
- |
Mus musculus |
Storage Stability
| EC Number | Storage Stability | Organism |
|---|---|---|
| 3.1.2.6 | -30°C, 1 mM S-octylglutathione, stable for 1 month | Mus musculus |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.1.2.6 | lactoylglutathione + H2O | S-D-lactoylglutathione | Mus musculus | D-lactate + glutathione | - |
? | |
| 3.1.2.6 | S-D-lactoylglutathione + H2O | - |
Mus musculus | D-lactate + glutathione | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 3.1.2.6 | monomer | 1 * 29500, SDS-PAGE | Mus musculus |
Turnover Number [1/s]
| EC Number | Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 3.1.2.6 | 450 | - |
S-D-lactoylglutathione | - |
Mus musculus | |
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Release 2023.1 (January 2023)
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