EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.1.13.1 | RNA with a 2',3'-cyclic phosphate group | on the potential substrate molecule | Mus musculus | |
3.1.13.1 | RNA with a terminal 3'-phosphate group | on the potential substrate molecule | Mus musculus | |
3.1.13.1 | thymidine nucleotides | potent inhibitor, pTp at a concentration of 0.00004 M inhibits degradation of poly(A) by 60%, pTpT at a concentration of 0.0005 M inhibits degradation of poly(A) by 30% | Mus musculus | |
3.1.13.1 | Urea | loss of 40% of activity in presence of 1.6 M, 60% in presence of 2.4 M and 75% in presence of 3.2 M urea | Mus musculus |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
3.1.13.1 | nucleus | - |
Mus musculus | 5634 | - |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.1.13.1 | ss RNA + H2O | Mus musculus | - |
5'-phosphomononucleotides | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.1.13.1 | Mus musculus | - |
mouse | - |
EC Number | Reaction | Comment | Organism | Reaction ID |
---|---|---|---|---|
3.1.13.1 | Exonucleolytic cleavage in the 3'- to 5'- direction to yield nucleoside 5'-phosphates | acts in a processive manner | Mus musculus |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
3.1.13.1 | breast adenocarcinoma cell | - |
Mus musculus | - |
3.1.13.1 | Ehrlich ascites carcinoma cell | - |
Mus musculus | - |
3.1.13.1 | embryo | - |
Mus musculus | - |
3.1.13.1 | kidney | - |
Mus musculus | - |
3.1.13.1 | liver | - |
Mus musculus | - |
EC Number | Storage Stability | Organism |
---|---|---|
3.1.13.1 | -70°C, more than 50% of activity after more than a year | Mus musculus |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.1.13.1 | additional information | 3'-phosphorylated RNA is not hydrolyzed | Mus musculus | ? | - |
? | |
3.1.13.1 | poly(A) + H2O | - |
Mus musculus | 5'-AMP + oligonucleotide | - |
? | |
3.1.13.1 | ss RNA + H2O | - |
Mus musculus | 5'-phosphomononucleotides | - |
? |
EC Number | Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|---|
3.1.13.1 | 50 | - |
in 0.1 M Tris-Cl, pH 8.0, for 15 min, loss of 20-30% of activity | Mus musculus |
3.1.13.1 | 50 | - |
in 0.1 M Tris-Cl, pH 8.0, for 60 min, loss of 40-60% of activity | Mus musculus |