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Literature summary extracted from

  • Steiner, M.
    Localization and characterization of phospholipase A2 in mouse mammary gland-derived cells (1991), Arch. Biochem. Biophys., 286, 293-299.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.1.4 3-[(3-cholamidopropyl)-dimethylammonio]-1-propanesulfonate
-
 Mus musculus
3.1.1.4 Nonidet-P40
-
 Mus musculus
3.1.1.4 sodium deoxycholate
-
 Mus musculus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.1.1.4 cytoplasm cells harvested in EGTA Mus musculus 5737
-
3.1.1.4 plasma membrane cells harvested in buffer containing free Ca2+ Mus musculus 5886
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.1.1.4 Ca2+ Ca2+-dependent association with cellular membranes Mus musculus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.1.4 phospholipids + H2O Mus musculus eicosanoids ?
-
 ?
3.1.1.4 phospholipids + H2O Mus musculus cancer ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.4 Mus musculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.1.4 breast adenocarcinoma cell
-
 Mus musculus
-
3.1.1.4 mammary gland
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.4 1-acyl-2-arachidonoyl-sn-glycerophosphocholine + H2O
-
 Mus musculus 1-acyl-sn-glycerophosphocholine + arachidonic acid
-
 ?
3.1.1.4 1-acyl-2-arachidonoyl-sn-glycerophosphoethanolamine + H2O
-
 Mus musculus 1-acyl-sn-glycerophosphoethanolamine + arachidonic acid
-
 ?
3.1.1.4 1-acyl-2-linoleoyl-sn-glycerophosphocholine + H2O
-
 Mus musculus 1-acyl-sn-glycerophosphocholine + linoleic acid
-
 ?
3.1.1.4 1-acyl-2-oleoyl-sn-glycerophosphocholine + H2O
-
 Mus musculus 1-acyl-sn-glycerophosphocholine + oleic acid
-
 ?
3.1.1.4 1-acyl-2-palmitoyl-sn-glycerophosphocholine + H2O
-
 Mus musculus 1-acyl-sn-glycerophosphocholine + palmitic acid
-
 ?
3.1.1.4 1-stearoyl-2-arachidonoylphosphatidylcholine + H2O
-
 Mus musculus 1-stearoyl-glycerophosphorylcholine + arachidonic acid
-
 ?
3.1.1.4 phosphatidylinositol + arachidonic acid
-
 Mus musculus arachidonoyl phosphatidylinositol + fatty acid
-
 ?
3.1.1.4 phospholipids + H2O eicosanoids Mus musculus ?
-
 ?
3.1.1.4 phospholipids + H2O cancer Mus musculus ?
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.1.1.4 8.1
-
 substrate: phosphatidylethanolamine, without DTT Mus musculus
3.1.1.4 9
-
 substrate: phosphatidylethanolamine, with DTT Mus musculus
3.1.1.4 9.5
-
 substrate: phosphatidylcholine, without DTT Mus musculus
3.1.1.4 9.7
-
 substrate: phosphatidylcholine, with DTT Mus musculus