EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.14.12.7 | 1,10-phenanthroline | - |
Burkholderia cepacia | |
1.14.12.7 | Cu2+ | - |
Burkholderia cepacia | |
1.14.12.7 | EDTA | - |
Burkholderia cepacia | |
1.14.12.7 | Zn2+ | - |
Burkholderia cepacia |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
1.14.12.7 | Fe3+ | stimulates | Burkholderia cepacia | |
1.14.12.7 | Iron | active form of enzyme contains one mononuclear iron and one [2Fe-2S] center per monomer | Burkholderia cepacia |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
1.14.12.7 | 48000 | - |
4 * 48000, SDS-PAGE | Burkholderia cepacia |
1.14.12.7 | 217000 | - |
gel filtration | Burkholderia cepacia |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.3.1.64 | cis-4,5-dihydroxycyclohexa-1(6),2-diene-1,2-dicarboxylate + NAD+ | Burkholderia cepacia | involved in the phthalate degradation pathway in bacteria | 4,5-dihydroxyphthalate + NADH + H+ | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.3.1.64 | Burkholderia cepacia | - |
- |
- |
1.14.12.7 | Burkholderia cepacia | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.3.1.64 | cis-4,5-dihydroxycyclohexa-1(6),2-diene-1,2-dicarboxylate + NAD+ | - |
Burkholderia cepacia | 4,5-dihydroxyphthalate + NADH + H+ | - |
? | |
1.3.1.64 | cis-4,5-dihydroxycyclohexa-1(6),2-diene-1,2-dicarboxylate + NAD+ | involved in the phthalate degradation pathway in bacteria | Burkholderia cepacia | 4,5-dihydroxyphthalate + NADH + H+ | - |
? | |
1.14.12.7 | 2,3-dicarboxypyridine + NADH + O2 | 69% of the activity with o-phthalate | Burkholderia cepacia | 5,6-dihydroxy-5,6-dihydropyridine-2,3-dicarboxylate + NAD+ + H2O | - |
? | |
1.14.12.7 | 4-chloro-o-phthalate + NADH + O2 | 79% of the activity with o-phthalate | Burkholderia cepacia | 4-chloro-cis-4,5-dihydroxycyclohexa-1(6),2-diene-1,2-dicarboxylate + NAD+ + H2O | - |
? | |
1.14.12.7 | phthalate + NADH + O2 | o-phthalate | Burkholderia cepacia | cis-4,5-dihydroxycyclohexa-1(6),2-diene-1,2-dicarboxylate + NAD+ + H2O | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
1.14.12.7 | tetramer | 4 * 48000, SDS-PAGE | Burkholderia cepacia |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.3.1.64 | NAD+ | - |
Burkholderia cepacia | |
1.3.1.64 | NADH | - |
Burkholderia cepacia | |
1.14.12.7 | FMN | enzyme contains FMN | Burkholderia cepacia | |
1.14.12.7 | NADH | - |
Burkholderia cepacia |