EC Number | Cloned (Comment) | Organism |
---|---|---|
6.3.2.4 | overproduction in Escherichia coli, the vancomycin resistant enzyme has Phe261 instead of Tyr. The Tyr to Phe substitution on the active site omega-loop in the D-Ala-D-Ala ligases is a molecular indicator of both the ability to make D-Ala-D-Lac and intrinsic resistance to the vancomycin class of glycopeptide antibiotics | Leuconostoc mesenteroides |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
6.3.2.4 | additional information | - |
additional information | - |
Leuconostoc mesenteroides |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
6.3.2.4 | Leuconostoc mesenteroides | P71454 | resistant to vancomycin | - |
EC Number | Purification (Comment) | Organism |
---|---|---|
6.3.2.4 | - |
Leuconostoc mesenteroides |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
6.3.2.4 | ATP + D-Ala + D-Ala | - |
Leuconostoc mesenteroides | ADP + phosphate + D-Ala-D-Ala | - |
? | |
6.3.2.4 | ATP + D-Ala + D-lactate | - |
Leuconostoc mesenteroides | ADP + phosphate + D-Ala-D-lactate | - |
? |
EC Number | Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
6.3.2.4 | additional information | - |
additional information | - |
Leuconostoc mesenteroides |