EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.1.3.25 | Li+ | at 100 mM 72% inhibition of the brain enzyme but only 27% of the duodenal enzyme | Rattus norvegicus |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
3.1.3.25 | 0.09 | - |
DL-myo-inositol 1-phosphate | brain IMPase | Rattus norvegicus | |
3.1.3.25 | 0.15 | - |
DL-myo-inositol 1-phosphate | duodenal IMPase | Rattus norvegicus | |
3.1.3.25 | 0.2 | - |
Glycerol 2-phosphate | duodenal IMPase | Rattus norvegicus | |
3.1.3.25 | 0.34 | - |
Glycerol 2-phosphate | brain IMPase | Rattus norvegicus |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
3.1.3.25 | Mg2+ | duodenal IMPase is less dependent on Mg2+ than the brain one | Rattus norvegicus |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
3.1.3.25 | 24000 | - |
2 * 24000, SDS-PAGE | Rattus norvegicus |
3.1.3.25 | 48000 | - |
gel filtration | Rattus norvegicus |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.1.3.25 | Rattus norvegicus | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
3.1.3.25 | 223fold | Rattus norvegicus |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
3.1.3.25 | brain | - |
Rattus norvegicus | - |
3.1.3.25 | duodenal mucosa | - |
Rattus norvegicus | - |
3.1.3.25 | ileal mucosa | - |
Rattus norvegicus | - |
3.1.3.25 | kidney | - |
Rattus norvegicus | - |
3.1.3.25 | lung | - |
Rattus norvegicus | - |
3.1.3.25 | pancreas | - |
Rattus norvegicus | - |
3.1.3.25 | stomach | - |
Rattus norvegicus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.1.3.25 | 3'-AMP + H2O | - |
Rattus norvegicus | adenosine + phosphate | - |
? | |
3.1.3.25 | 4-nitrophenyl phosphate + H2O | - |
Rattus norvegicus | 4-nitrophenol + phosphate | - |
? | |
3.1.3.25 | DL-myo-inositol 1-phosphate + H2O | - |
Rattus norvegicus | DL-myo-inositol + phosphate | - |
? | |
3.1.3.25 | glycerol 2-phosphate + H2O | - |
Rattus norvegicus | glycerol + phosphate | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
3.1.3.25 | dimer | 2 * 24000, SDS-PAGE | Rattus norvegicus |
EC Number | Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|---|
3.1.3.25 | 75 | - |
for 10 min, the duodenal enzyme retains only 27% of activity, the brain enzyme 67% | Rattus norvegicus |