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Literature summary extracted from
- Human erythrocyte acetylcholinesterase; purification, properties and kinetic behavior (1972), Biochim. Biophys. Acta, 284, 136-156.
General Stability
| EC Number | General Stability | Organism |
|---|---|---|
| 3.1.1.7 | 50% loss of activity, 3 hours, dialysis against deionized water | Homo sapiens |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.1.1.7 | acetylthiocholine iodide | above 5 mM | Homo sapiens |  |
| 3.1.1.7 | choline | - |
Homo sapiens | |
| 3.1.1.7 | F- | - |
Homo sapiens | |
| 3.1.1.7 | Tetramethyl ammonium | - |
Homo sapiens | |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 3.1.1.7 | 0.18 | - |
acetylthiocholine iodide | - |
Homo sapiens | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.1.1.7 | Homo sapiens | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 3.1.1.7 | - |
Homo sapiens |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.1.1.7 | erythrocyte | - |
Homo sapiens | - |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 3.1.1.7 | 29.6 | - |
- |
Homo sapiens |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.1.1.7 | acetylcholine + H2O | - |
Homo sapiens | choline + acetate | - |
? | |
| 3.1.1.7 | alpha-naphthyl acetate + H2O | - |
Homo sapiens | alpha-naphthol + acetate | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 3.1.1.7 | polymer | - |
Homo sapiens |
Temperature Optimum [°C]
| EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 3.1.1.7 | additional information | - |
- |
Homo sapiens |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 3.1.1.7 | 4.8 | 8.5 | - |
Homo sapiens |
pH Stability
| EC Number | pH Stability | pH Stability Maximum | Comment | Organism |
|---|---|---|---|---|
| 3.1.1.7 | 4 | 9 | activity loss below pH 4.0 and above pH 9.0 | Homo sapiens |
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Release 2023.1 (January 2023)
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