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Literature summary extracted from

  • Simondsen, R.P.; Meister, A.
    Interaction of the D-isomer of gamma-methylene glutamate with an active site thiol of gamma-glutamylcysteine synthetase (1986), J. Biol. Chem., 261, 17134-17137.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
6.3.2.2 gamma-Methylglutamate D-isomer inhibits, L-isomer not, competitively towards Glu, inactivation is dependent upon the presence of Mg2+ or Mn2+, Glu protects against inactivation Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
6.3.2.2 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
6.3.2.2 kidney
-
Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.3.2.2 ATP + L-Glu + L-Cys
-
Rattus norvegicus ADP + phosphate + gamma-L-Glu-L-Cys
-
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