EC Number | Cloned (Comment) | Organism |
---|---|---|
6.3.2.17 | overexpression in Escherichia coli | Homo sapiens |
6.3.2.17 | overexpression in Escherichia coli | Saccharomyces cerevisiae |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
6.3.2.17 | cytosol | - |
eukaryota | 5829 | - |
6.3.2.17 | cytosol | - |
Homo sapiens | 5829 | - |
6.3.2.17 | mitochondrion | - |
eukaryota | 5739 | - |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
6.3.2.17 | K+ | maximal activity at 20 mM | Homo sapiens | |
6.3.2.17 | K+ | maximal activity at 20 mM | Sus scrofa | |
6.3.2.17 | K+ | maximal activity at 20 mM | Saccharomyces cerevisiae | |
6.3.2.17 | K+ | required form maximal activity | Escherichia coli | |
6.3.2.17 | K+ | required form maximal activity | Homo sapiens | |
6.3.2.17 | K+ | required form maximal activity | Sus scrofa | |
6.3.2.17 | K+ | required form maximal activity | Saccharomyces cerevisiae | |
6.3.2.17 | K+ | required form maximal activity | Corynebacterium sp. | |
6.3.2.17 | K+ | required form maximal activity | Lacticaseibacillus casei | |
6.3.2.17 | K+ | maximal activity at 200 mM | Escherichia coli | |
6.3.2.17 | K+ | maximal activity at 200 mM | Sus scrofa | |
6.3.2.17 | K+ | maximal activity at 200 mM | Corynebacterium sp. | |
6.3.2.17 | K+ | maximal activity at 200 mM | Lacticaseibacillus casei | |
6.3.2.17 | Mg2+ | required | Escherichia coli | |
6.3.2.17 | Mg2+ | required | Homo sapiens | |
6.3.2.17 | Mg2+ | required | Sus scrofa | |
6.3.2.17 | Mg2+ | required | Saccharomyces cerevisiae | |
6.3.2.17 | Mg2+ | required | Corynebacterium sp. | |
6.3.2.17 | Mg2+ | required | Lacticaseibacillus casei |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
6.3.2.17 | 62000 | - |
- |
Saccharomyces cerevisiae |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
6.3.2.17 | additional information | Homo sapiens | enzyme catalyzes the addition of glutamate residues to folates and antifolates to form the physiological active coenzymatic forms of the vitamin and more potent anti-folate agents | ? | - |
? | |
6.3.2.17 | additional information | Saccharomyces cerevisiae | enzyme catalyzes the addition of glutamate residues to folates and antifolates to form the physiological active coenzymatic forms of the vitamin and more potent anti-folate agents | ? | - |
? | |
6.3.2.17 | additional information | eukaryota | mitochondrial enzyme is required for mitochondrial one carbon metabolism and for normal one carbon flux in the cytosol | ? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
6.3.2.17 | Corynebacterium sp. | - |
- |
- |
6.3.2.17 | Escherichia coli | - |
- |
- |
6.3.2.17 | eukaryota | - |
- |
- |
6.3.2.17 | Homo sapiens | - |
- |
- |
6.3.2.17 | Lacticaseibacillus casei | - |
- |
- |
6.3.2.17 | Saccharomyces cerevisiae | - |
- |
- |
6.3.2.17 | Sus scrofa | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
6.3.2.17 | additional information | enzyme also posseses dihydrofolate synthetase activity | Escherichia coli | ? | - |
? | |
6.3.2.17 | additional information | enzyme also posseses dihydrofolate synthetase activity | Corynebacterium sp. | ? | - |
? | |
6.3.2.17 | additional information | no dihydrofolate synthetase activity | Homo sapiens | ? | - |
? | |
6.3.2.17 | additional information | no dihydrofolate synthetase activity | Sus scrofa | ? | - |
? | |
6.3.2.17 | additional information | no dihydrofolate synthetase activity | Saccharomyces cerevisiae | ? | - |
? | |
6.3.2.17 | additional information | no dihydrofolate synthetase activity | Lacticaseibacillus casei | ? | - |
? | |
6.3.2.17 | additional information | enzyme catalyzes the addition of glutamate residues to folates and antifolates to form the physiological active coenzymatic forms of the vitamin and more potent anti-folate agents | Homo sapiens | ? | - |
? | |
6.3.2.17 | additional information | enzyme catalyzes the addition of glutamate residues to folates and antifolates to form the physiological active coenzymatic forms of the vitamin and more potent anti-folate agents | Saccharomyces cerevisiae | ? | - |
? | |
6.3.2.17 | additional information | mitochondrial enzyme is required for mitochondrial one carbon metabolism and for normal one carbon flux in the cytosol | eukaryota | ? | - |
? |
EC Number | Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
6.3.2.17 | additional information | - |
additional information | - |
Escherichia coli | |
6.3.2.17 | additional information | - |
additional information | - |
Homo sapiens | |
6.3.2.17 | additional information | - |
additional information | - |
Sus scrofa | |
6.3.2.17 | additional information | - |
additional information | - |
Corynebacterium sp. | |
6.3.2.17 | additional information | - |
additional information | - |
Lacticaseibacillus casei |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
6.3.2.17 | 9.4 | - |
- |
Escherichia coli |
6.3.2.17 | 9.4 | - |
- |
Homo sapiens |
6.3.2.17 | 9.4 | - |
- |
Sus scrofa |
6.3.2.17 | 9.5 | - |
- |
Sus scrofa |
6.3.2.17 | 9.5 | - |
- |
Saccharomyces cerevisiae |
6.3.2.17 | 9.5 | - |
- |
Corynebacterium sp. |
6.3.2.17 | 9.5 | - |
- |
Lacticaseibacillus casei |