Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 7.6.2.4 extracted from

  • van Roermund, C.W.; Visser, W.F.; Ijlst, L.; van Cruchten, A.; Boek, M.; Kulik, W.; Waterham, H.R.; Wanders, R.J.
    The human peroxisomal ABC half transporter ALDP functions as a homodimer and accepts acyl-CoA esters (2008), FASEB J., 22, 4201-4208.
    View publication on PubMed
Search for more literature for 7.6.2.4

Cloned(Commentary)

Cloned (Comment) Organism
gene ABCD1, DNA and amino oacid sequence determination and analysis Saccharomyces cerevisiae

Localization

Localization Comment Organism GeneOntology No. Textmining
peroxisomal membrane two peroxisomal half ABC transporters Pxa1p and Pxa2p form a heterodimeric complex in the peroxisomal membrane Saccharomyces cerevisiae 5778
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O + fatty acyl-CoA/cis Saccharomyces cerevisiae specificity of the two different uptake routes in peroxisomal beta-oxidation of fatty acids, overview ADP + phosphate + fatty acyl-CoA/trans
-
 ?
ATP + H2O + fatty acyl-CoA/cis Saccharomyces cerevisiae BJ1991 specificity of the two different uptake routes in peroxisomal beta-oxidation of fatty acids, overview ADP + phosphate + fatty acyl-CoA/trans
-
 ?

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
 gene ABCD1
-
Saccharomyces cerevisiae BJ1991
-
 gene ABCD1
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + fatty acyl-CoA/cis specificity of the two different uptake routes in peroxisomal beta-oxidation of fatty acids, overview Saccharomyces cerevisiae ADP + phosphate + fatty acyl-CoA/trans
-
 ?
ATP + H2O + fatty acyl-CoA/cis ALDP can function as a homodimer and accepts a range of acyl-CoA esters Saccharomyces cerevisiae ADP + phosphate + fatty acyl-CoA/trans
-
 ?
ATP + H2O + fatty acyl-CoA/cis specificity of the two different uptake routes in peroxisomal beta-oxidation of fatty acids, overview Saccharomyces cerevisiae BJ1991 ADP + phosphate + fatty acyl-CoA/trans
-
 ?
ATP + H2O + fatty acyl-CoA/cis ALDP can function as a homodimer and accepts a range of acyl-CoA esters Saccharomyces cerevisiae BJ1991 ADP + phosphate + fatty acyl-CoA/trans
-
 ?
ATP + H2O + heptadecanoyl-CoA/cis
-
 Saccharomyces cerevisiae ADP + phosphate + heptadecanoyl-CoA/trans
-
 ?
ATP + H2O + heptadecanoyl-CoA/cis
-
 Saccharomyces cerevisiae BJ1991 ADP + phosphate + heptadecanoyl-CoA/trans
-
 ?

Subunits

Subunits Comment Organism
heterodimer two peroxisomal half ABC transporters Pxa1p and Pxa2p form a heterodimeric complex in the peroxisomal membrane Saccharomyces cerevisiae
homodimer ALDP can function as a homodimer and accepts a range of acyl-CoA esters Saccharomyces cerevisiae

Synonyms

Synonyms Comment Organism
ABC half transporter
-
 Saccharomyces cerevisiae
ALDP
-
 Saccharomyces cerevisiae
Pxa1p
-
 Saccharomyces cerevisiae
Pxa2p
-
 Saccharomyces cerevisiae

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Saccharomyces cerevisiae