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Literature summary for 7.6.2.4 extracted from

  • Contreras, M.; Sengupta, T.K.; Sheikh, F.; Aubourg, P.; Singh, I.
    Topology of ATP-binding domain of adrenoleukodystrophy gene product in peroxisomes (1996), Arch. Biochem. Biophys., 334, 369-379.
    View publication on PubMed
Search for more literature for 7.6.2.4

Localization

Localization Comment Organism GeneOntology No. Textmining
peroxisome enzyme contains six membrane-spanning segments and a putative ATP-binding domain, the C-terminal hydrophilic domain of the enzyme is on the cytoplasmic surface of peroxisomes Rattus norvegicus 5777
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Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
75000
-
 x * 75000, SDS-PAGE Rattus norvegicus
84000
-
 x * 84000, calculation from amino acid sequence Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O + fatty acyl CoA/cis Rattus norvegicus a defect in the gene for fatty-acyl-CoA-transporting ATPase is responsible for adrenoleukodystrophy, a demyelinating disorder characterized by the accumulation of saturated very-long-chain fatty acids ADP + phosphate + fatty acyl CoA/trans
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
ATP-binding domain Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + fatty acyl CoA/cis
-
 Rattus norvegicus ADP + phosphate + fatty acyl CoA/trans
-
 ?
ATP + H2O + fatty acyl CoA/cis a defect in the gene for fatty-acyl-CoA-transporting ATPase is responsible for adrenoleukodystrophy, a demyelinating disorder characterized by the accumulation of saturated very-long-chain fatty acids Rattus norvegicus ADP + phosphate + fatty acyl CoA/trans
-
 ?

Subunits

Subunits Comment Organism
? x * 75000, SDS-PAGE Rattus norvegicus
? x * 84000, calculation from amino acid sequence Rattus norvegicus