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Literature summary for 7.6.2.3 extracted from

  • Vaidya, S.; Walsh, S.; Gerk, P.
    Formation and efflux of ATP-binding cassette transporter substrate 2,4-dinitrophenyl-S-glutathione from cultured human term placental villous tissue fragments (2009), Mol. Pharm., 6, 1689-1702 .
    View publication on PubMed
Search for more literature for 7.6.2.3

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Sf9 insect cells Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
dipyridamole
-
 Homo sapiens
MK571
-
 Homo sapiens
sodium orthovanadate
-
 Homo sapiens
verapamil
-
 Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
plasma membrane
-
 Homo sapiens 5886
-

Organism

Organism UniProt Comment Textmining
Homo sapiens P33527
-
-
Homo sapiens Q92887
-
-

Source Tissue

Source Tissue Comment Organism Textmining
chorionic villus
-
 Homo sapiens
-
placenta
-
 Homo sapiens
-
syncytiotrophoblast
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + 2,4-dinitrophenyl-S-glutathione[side 1]
-
 Homo sapiens ADP + phosphate + 2,4-dinitrophenyl-S-glutathione[side 2]
-
 ?

Subunits

Subunits Comment Organism
? x * 190000, calculated from amino acid sequence Homo sapiens

Synonyms

Synonyms Comment Organism
MRP1
-
 Homo sapiens
MRP2
-
 Homo sapiens
multidrug resistance-associated protein
-
 Homo sapiens