Literature summary for 7.6.2.2 extracted from

Guan, G.F.; Zhang, D.J.; Zheng, Y.; Wen, L.J.; Yu, D.J.; Lu, Y.Q.; Zhao, Y.
Significance of ATP-binding cassette transporter proteins in multidrug resistance of head and neck squamous cell carcinoma (2015), Oncol. Lett., 10, 631-636 .

Search for more literature for 7.6.2.2

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	Q9UNQ0	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
head and neck squamous carcinoma cell	-	Homo sapiens	-
HNSCC cell	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + H2O + Hoechst33342[side 1]	-	Homo sapiens	ADP + phosphate + Hoechst33342[side 2]	-	?
ATP + H2O + verapamil[side 1]	-	Homo sapiens	ADP + phosphate + verapamil[side 2]	-	?

Synonyms

Synonyms	Comment	Organism
ABCG2	-	Homo sapiens
ATP-binding cassette transporter	-	Homo sapiens

General Information

General Information	Comment	Organism
physiological function	the enzyme may be responsible for chemotherapy failure and tumor relapse in patients with head and neck squamous cell carcinoma	Homo sapiens

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Release 2023.1 (January 2023)