Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
plasma membrane | - |
Plasmodium falciparum | 5886 | - |
plasma membrane | - |
Plasmodium berghei | 5886 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Plasmodium berghei | - |
- |
- |
Plasmodium falciparum | - |
- |
- |
Plasmodium falciparum | P13568 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
sporozoite | - |
Plasmodium falciparum | - |
sporozoite | - |
Plasmodium berghei | - |
Synonyms | Comment | Organism |
---|---|---|
MDR1 | isoform | Plasmodium berghei |
MDR1 | isoform | Plasmodium falciparum |
Mdr2 | isoform | Plasmodium falciparum |
Mdr2 | isoform | Plasmodium berghei |
Mdr3 | isoform | Plasmodium falciparum |
Mdr3 | isoform | Plasmodium berghei |
MDR4 | isoform | Plasmodium falciparum |
MDR4 | isoform | Plasmodium berghei |
MDR5 | isoform | Plasmodium falciparum |
MDR5 | isoform | Plasmodium berghei |
MDR6 | isoform | Plasmodium falciparum |
MDR6 | isoform | Plasmodium berghei |
MDR7 | isoform | Plasmodium falciparum |
MDR7 | isoform | Plasmodium berghei |
multidrug resistance transporter | - |
Plasmodium falciparum |
multidrug resistance transporter | - |
Plasmodium berghei |
General Information | Comment | Organism |
---|---|---|
malfunction | mutants lacking isoforms MDR3 and MDR5 have a reduced blood stage multiplication in vivo. Oocyst maturation and sporozoite formation in Plasmodium mutants lacking isoforms MDR2 or MDR5 is reduced | Plasmodium berghei |
physiological function | the enzyme plays a vital and dispensable role during blood stages | Plasmodium falciparum |
physiological function | the enzyme plays a vital and dispensable role during blood stages. Isoforms MDR2 and MDR5 have important functions in sporogony as well as sporozoite development | Plasmodium falciparum |
physiological function | the enzyme plays a vital and dispensable role during blood stages. Isoforms MDR2 and MDR5 have important functions in sporogony as well as sporozoite development | Plasmodium berghei |