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Literature summary for 7.6.2.2 extracted from
- Structural biology meets drug resistance an overview on multidrug resistance transporters (2017), J. Indian Inst. Sci., 97, 165-175 .
No PubMed abstract available
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| plasma membrane | - |
Staphylococcus aureus | 5886 | - |
| plasma membrane | - |
Bacillus subtilis | 5886 | - |
| plasma membrane | - |
Mus musculus | 5886 | - |
| plasma membrane | - |
Pseudomonas aeruginosa | 5886 | - |
| plasma membrane | - |
Salmonella enterica | 5886 | - |
| plasma membrane | - |
Escherichia coli | 5886 | - |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + H2O + xenobiotic[side 1] | Staphylococcus aureus | - |
ADP + phosphate + xenobiotic[side 2] | - |
? |  |
| ATP + H2O + xenobiotic[side 1] | Bacillus subtilis | - |
ADP + phosphate + xenobiotic[side 2] | - |
? | |
| ATP + H2O + xenobiotic[side 1] | Mus musculus | - |
ADP + phosphate + xenobiotic[side 2] | - |
? | |
| ATP + H2O + xenobiotic[side 1] | Pseudomonas aeruginosa | - |
ADP + phosphate + xenobiotic[side 2] | - |
? | |
| ATP + H2O + xenobiotic[side 1] | Salmonella enterica | - |
ADP + phosphate + xenobiotic[side 2] | - |
? | |
| ATP + H2O + xenobiotic[side 1] | Escherichia coli | - |
ADP + phosphate + xenobiotic[side 2] | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bacillus subtilis | - |
- |
- |
| Escherichia coli | P0AEY8 | - |
- |
| Mus musculus | - |
- |
- |
| Pseudomonas aeruginosa | - |
- |
- |
| Salmonella enterica | - |
- |
- |
| Staphylococcus aureus | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + H2O + xenobiotic[side 1] | - |
Staphylococcus aureus | ADP + phosphate + xenobiotic[side 2] | - |
? | |
| ATP + H2O + xenobiotic[side 1] | - |
Bacillus subtilis | ADP + phosphate + xenobiotic[side 2] | - |
? | |
| ATP + H2O + xenobiotic[side 1] | - |
Mus musculus | ADP + phosphate + xenobiotic[side 2] | - |
? | |
| ATP + H2O + xenobiotic[side 1] | - |
Pseudomonas aeruginosa | ADP + phosphate + xenobiotic[side 2] | - |
? | |
| ATP + H2O + xenobiotic[side 1] | - |
Salmonella enterica | ADP + phosphate + xenobiotic[side 2] | - |
? | |
| ATP + H2O + xenobiotic[side 1] | - |
Escherichia coli | ADP + phosphate + xenobiotic[side 2] | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| ABC multidrug efflux transporter | - |
Staphylococcus aureus |
| ABC multidrug efflux transporter | - |
Bacillus subtilis |
| ABC multidrug efflux transporter | - |
Mus musculus |
| ABC multidrug efflux transporter | - |
Pseudomonas aeruginosa |
| ABC multidrug efflux transporter | - |
Salmonella enterica |
| ABC multidrug efflux transporter | - |
Escherichia coli |
| AcrB | - |
Pseudomonas aeruginosa |
| AcrB | - |
Salmonella enterica |
| acriflavine resistance protein | - |
Pseudomonas aeruginosa |
| acriflavine resistance protein | - |
Salmonella enterica |
| Bmr | - |
Bacillus subtilis |
| MdfA | - |
Escherichia coli |
| MDR transporter | - |
Staphylococcus aureus |
| MDR transporter | - |
Bacillus subtilis |
| MDR transporter | - |
Mus musculus |
| MDR transporter | - |
Pseudomonas aeruginosa |
| MDR transporter | - |
Salmonella enterica |
| MDR transporter | - |
Escherichia coli |
| multidrug resistance transporter | - |
Staphylococcus aureus |
| multidrug resistance transporter | - |
Bacillus subtilis |
| multidrug resistance transporter | - |
Mus musculus |
| multidrug resistance transporter | - |
Pseudomonas aeruginosa |
| multidrug resistance transporter | - |
Salmonella enterica |
| multidrug resistance transporter | - |
Escherichia coli |
| P-glycoprotein | - |
Mus musculus |
| P-gp | - |
Mus musculus |
| Sav1886 | - |
Staphylococcus aureus |
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