Literature summary for 7.6.2.2 extracted from

Teixeira, M.C.; Godinho, C.P.; Cabrito, T.R.; Mira, N.P.; Sa-Correia, I.
Increased expression of the yeast multidrug resistance ABC transporter Pdr18 leads to increased ethanol tolerance and ethanol production in high gravity alcoholic fermentation (2012), Microb. Cell Fact., 11, 98.

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Application

Application	Comment	Organism
biofuel production	gene overexpression in industrial yeast strains improves the alcoholic fermentation performance for sustainable bio-ethanol production	Saccharomyces cerevisiae

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
plasma membrane	-	Saccharomyces cerevisiae	5886	-

Organism

Organism	UniProt	Comment	Textmining
Saccharomyces cerevisiae	-	-	-
Saccharomyces cerevisiae BY4741	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + H2O + ethanol/in	-	Saccharomyces cerevisiae	ADP + phosphate + ethanol/out	-	?
ATP + H2O + ethanol/in	-	Saccharomyces cerevisiae BY4741	ADP + phosphate + ethanol/out	-	?

Synonyms

Synonyms	Comment	Organism
multidrug resistance ABC transporter	-	Saccharomyces cerevisiae
Pdr18	-	Saccharomyces cerevisiae

General Information

General Information	Comment	Organism
physiological function	the enzyme confers resistance to growth inhibitory concentrations of ethanol. Enzyme expression decreases intracellular ethanol accumulation and ethanol-induced plasma membrane permeabilization	Saccharomyces cerevisiae

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Release 2023.1 (January 2023)