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Literature summary for 7.6.2.2 extracted from
- Tissue distribution and ontogeny of multidrug resistance protein 2, a phosphatidylcholine translocator, in rats (2016), Eur. J. Drug Metab. Pharmacokinet., 41, 87-91.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + H2O + phosphatidylcholine/in | Rattus norvegicus | - |
ADP + phosphate + phosphatidylcholine/out | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | Q08201 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | - |
Rattus norvegicus | - |
| jejunum | - |
Rattus norvegicus | - |
| liver | highest expression | Rattus norvegicus | - |
| spleen | - |
Rattus norvegicus | - |
| testis | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + H2O + phosphatidylcholine/in | - |
Rattus norvegicus | ADP + phosphate + phosphatidylcholine/out | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Mdr2 | - |
Rattus norvegicus |
| multidrug resistance protein 2 | - |
Rattus norvegicus |
| phosphatidylcholine translocator | - |
Rattus norvegicus |
Expression
| Organism | Comment | Expression |
|---|---|---|
| Rattus norvegicus | the Mdr2 protein is not detected in livers from male and female rats at birth while mRNA is consistently expressed in livers at a high and steady level until 30 days of age | up |
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