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Literature summary for 7.6.2.2 extracted from

  • Wesolowska, O.; Wisniewski, J.; Sroda, K.; Krawczenko, A.; Bielawska-Pohl, A.; Paprocka, M.; Dus, D.; Michalak, K.
    8-Prenylnaringenin is an inhibitor of multidrug resistance-associated transporters, P-glycoprotein and MRP1 (2010), Eur. J. Pharmacol., 644, 32-40.
    View publication on PubMed
Search for more literature for 7.6.2.2

Inhibitors

Inhibitors Comment Organism Structure
8-prenylnaringenin
-
 Homo sapiens
verapamil
-
 Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
colonic adenocarcinoma cell line
-
 Homo sapiens
-
erythrocyte
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + 2',7'-bis(carboxyethyl)-5(6)-carboxyfluorescein/in
-
 Homo sapiens ADP + phosphate + 2',7'-bis(carboxyethyl)-5(6)-carboxyfluorescein/out
-
 ?
ATP + H2O + doxorubicin/in
-
 Homo sapiens ADP + phosphate + doxorubicin/out
-
 ?