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Literature summary for 7.6.2.2 extracted from

  • Iwanaga, K.; Hayashi, M.; Hamahata, Y.; Miyazaki, M.; Shibano, M.; Taniguchi, M.; Baba, K.; Kakemi, M.
    Furanocoumarin derivatives in Kampo extract medicines inhibit cytochrome P450 3A4 and P-glycoprotein (2010), Drug Metab. Dispos., 38, 1286-1294.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
byakangelicol shows strong P-gp inhibition from the screening of P-gp inhibitor evaluated by quinidine permeation through the Caco-2 monolayer Homo sapiens
rivulobirin A shows strong P-gp inhibition from the screening of P-gp inhibitor evaluated by quinidine permeation through the Caco-2 monolayer Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
Caco-2 cell
-
Homo sapiens
-

Synonyms

Synonyms Comment Organism
P-glycoprotein
-
Homo sapiens