Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(17beta)-N-([trans-4-[(6-amino-9H-purin-9-yl)methyl]cyclohexyl]methyl)-3-oxoandrost-4-ene-17-carboxamide | daunorubicin accumulation is 99% of the accumulation in presence of 0.01 mM progesterone | Homo sapiens | |
(17beta)-N-[(2E)-4-(6-amino-9H-purin-9-yl)but-2-en-1-yl]-3-oxoandrost-4-ene-17-carboxamide | daunorubicin accumulation is 72% of the accumulation in presence of 0.01 mM progesterone | Homo sapiens | |
(17beta)-N-[(2Z)-4-(6-amino-9H-purin-9-yl)but-2-en-1-yl]-3-oxoandrost-4-ene-17-carboxamide | daunorubicin accumulation is 86% of the accumulation in presence of 0.01 mM progesterone | Homo sapiens | |
(17beta)-N-[4-(6-amino-9H-purin-9-yl)but-2-yn-1-yl]-3-oxoandrost-4-ene-17-carboxamide | daunorubicin accumulation is 61% of the accumulation in presence of 0.01 mM progesterone | Homo sapiens | |
(17beta)-N-[4-(6-amino-9H-purin-9-yl)butyl]-3-oxoandrost-4-ene-17-carboxamide | daunorubicin accumulation is 78% of the accumulation in presence of 0.01 mM progesterone | Homo sapiens | |
(17beta)-N-[4-[(6-amino-9H-purin-9-yl)methyl]benzyl]-3-oxoandrost-4-ene-17-carboxamide | daunorubicin accumulation is 98% of the accumulation in presence of 0.01 mM progesterone | Homo sapiens | |
(17beta)-N-[6-(6-amino-9H-purin-9-yl)hexyl]-3-oxoandrost-4-ene-17-carboxamide | daunorubicin accumulation is 111% of the accumulation in presence of 0.01 mM progesterone | Homo sapiens | |
progesterone | - |
Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
K-562/R7 cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O + daunorubicin/in | - |
Homo sapiens | ADP + phosphate + daunorubicin/out | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ABCB1 | - |
Homo sapiens |
P-glycoprotein | - |
Homo sapiens |