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Literature summary for 7.6.2.2 extracted from

  • Kolaczkowski, M.; Kolaczkowska, A.; Sroda, K.; Ramalhete, C.; Michalak, K.; Mulhovo, S.; Ferreira, M.J.
    Substrates and modulators of the multidrug transporter Cdr1p of Candida albicans in antifungal extracts of medicinal plants (2010), Mycoses, 53, 305-310.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
gene cdr1, overexpression in Saccharaomyces cerevisiae Candida albicans
gene cdr1, overexpression in Saccharaomyces cerevisiae [Candida] glabrata

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O + xenobiotic/in Candida albicans
-
ADP + phosphate + xenobiotic/out
-
?
ATP + H2O + xenobiotic/in [Candida] glabrata
-
ADP + phosphate + xenobiotic/out
-
?
ATP + H2O + xenobiotic/in Candida albicans CCM8320
-
ADP + phosphate + xenobiotic/out
-
?
ATP + H2O + xenobiotic/in [Candida] glabrata CCM8270
-
ADP + phosphate + xenobiotic/out
-
?
additional information Candida albicans the recombinant enzyme in Saccharomyces cerevisiae is able to detoxify extracts of diverse plants collected in Mozambique, detailed overview ?
-
?
additional information [Candida] glabrata the recombinant enzyme in Saccharomyces cerevisiae is able to detoxify extracts of diverse plants collected in Mozambique, detailed overview ?
-
?
additional information Candida albicans CCM8320 the recombinant enzyme in Saccharomyces cerevisiae is able to detoxify extracts of diverse plants collected in Mozambique, detailed overview ?
-
?
additional information [Candida] glabrata CCM8270 the recombinant enzyme in Saccharomyces cerevisiae is able to detoxify extracts of diverse plants collected in Mozambique, detailed overview ?
-
?

Organism

Organism UniProt Comment Textmining
Candida albicans
-
-
-
Candida albicans CCM8320
-
-
-
[Candida] glabrata
-
-
-
[Candida] glabrata CCM8270
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + ketoconazole/in substrate from a ethyl acetate extract of Trichilia emetica leaves and seeds Candida albicans ADP + phosphate + ketoconazole/out
-
?
ATP + H2O + ketoconazole/in substrate from a ethyl acetate extract of Trichilia emetica leaves and seeds [Candida] glabrata ADP + phosphate + ketoconazole/out
-
?
ATP + H2O + ketoconazole/in substrate from a ethyl acetate extract of Trichilia emetica leaves and seeds Candida albicans CCM8320 ADP + phosphate + ketoconazole/out
-
?
ATP + H2O + ketoconazole/in substrate from a ethyl acetate extract of Trichilia emetica leaves and seeds [Candida] glabrata CCM8270 ADP + phosphate + ketoconazole/out
-
?
ATP + H2O + xenobiotic/in
-
Candida albicans ADP + phosphate + xenobiotic/out
-
?
ATP + H2O + xenobiotic/in
-
[Candida] glabrata ADP + phosphate + xenobiotic/out
-
?
ATP + H2O + xenobiotic/in
-
Candida albicans CCM8320 ADP + phosphate + xenobiotic/out
-
?
ATP + H2O + xenobiotic/in
-
[Candida] glabrata CCM8270 ADP + phosphate + xenobiotic/out
-
?
additional information the recombinant enzyme in Saccharomyces cerevisiae is able to detoxify extracts of diverse plants collected in Mozambique, detailed overview Candida albicans ?
-
?
additional information the recombinant enzyme in Saccharomyces cerevisiae is able to detoxify extracts of diverse plants collected in Mozambique, detailed overview [Candida] glabrata ?
-
?
additional information the recombinant enzyme in Saccharomyces cerevisiae is able to detoxify extracts of diverse plants collected in Mozambique, detailed overview Candida albicans CCM8320 ?
-
?
additional information the recombinant enzyme in Saccharomyces cerevisiae is able to detoxify extracts of diverse plants collected in Mozambique, detailed overview [Candida] glabrata CCM8270 ?
-
?

Synonyms

Synonyms Comment Organism
Cdr1p
-
Candida albicans
Cdr1p
-
[Candida] glabrata
More Cdr1p is a multidrug transporter of the ATP-binding cassette superfamily Candida albicans
More Cdr1p is a multidrug transporter of the ATP-binding cassette superfamily [Candida] glabrata
multidrug transporter
-
Candida albicans
multidrug transporter
-
[Candida] glabrata