Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | binding of drugs to Pgp is not compatible with a classical key-lock or one-pharmacophore model but can be well explained with a modular binding concept, where the energetically most relevant binding module seems to consist of two hydrogen bond acceptor groups | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | binding of drugs to Pgp is not compatible with a classical key-lock or one-pharmacophore model but can be well explained with a modular binding concept, where the energetically most relevant binding module seems to consist of two hydrogen bond acceptor groups | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ABCB1 | - |
Homo sapiens |
MDR1 | - |
Homo sapiens |
P-glycoprotein-ATPase | - |
Homo sapiens |