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Literature summary for 7.6.2.2 extracted from

  • Fernandez-Moreno, M.A.; Carbo, L.; Cuesta, T.; Vallin, C.; Malpartida, F.
    A silent ABC transporter isolated from Streptomyces rochei F20 induces multidrug resistance (1998), J. Bacteriol., 180, 4017-4023.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
ORF1 and ORF2 are simultaneously required for an efficient induction of the multidrug resistance phenotype Streptomyces rochei

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Streptomyces rochei
-
-
-
Streptomyces rochei F20
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
chloramphenicol/in + ATP + H2O
-
Streptomyces rochei chloramphenicol/out + ADP + phosphate
-
?
doxorubicin/in + ATP + H2O
-
Homo sapiens doxorubicin/out + ADP + phosphate
-
?
doxorubicin/in + ATP + H2O
-
Streptomyces rochei doxorubicin/out + ADP + phosphate
-
?
doxorubicin/in + ATP + H2O
-
Streptomyces rochei F20 doxorubicin/out + ADP + phosphate
-
?
erythromycin/in + ATP + H2O
-
Streptomyces rochei erythromycin/out + ADP + phosphate
-
?
erythromycin/in + ATP + H2O
-
Streptomyces rochei F20 erythromycin/out + ADP + phosphate
-
?
ethidium bromide/in + ATP + H2O
-
Streptomyces rochei ethidium bromide/out + ADP + phosphate
-
?
novobiocin/in + ATP + H2O
-
Streptomyces rochei novobiocin/out + ADP + phosphate
-
?
oleandomycin/in + ATP + H2O
-
Streptomyces rochei oleandomycin/out + ADP + phosphate
-
?
oleandomycin/in + ATP + H2O
-
Streptomyces rochei F20 oleandomycin/out + ADP + phosphate
-
?
pentachlorophenol/in + ATP + H2O
-
Streptomyces rochei pentachlorophenol/out + ADP + phosphate
-
?
phenol/in + ATP + H2O
-
Streptomyces rochei phenol/out + ADP + phosphate
-
?
spiramycin/in + ATP + H2O
-
Streptomyces rochei spiramycin/out + ADP + phosphate
-
?
spiramycin/in + ATP + H2O
-
Streptomyces rochei F20 spiramycin/out + ADP + phosphate
-
?
streptomycin/in + ATP + H2O
-
Streptomyces rochei streptomycin/out + ADP + phosphate
-
?
streptothricin/in + ATP + H2O
-
Streptomyces rochei streptothricin/out + ADP + phosphate
-
?
tetrachlorohydroquinone/in + ATP + H2O
-
Streptomyces rochei tetrachlorohydroquinone/out + ADP + phosphate
-
?
tetracyclin/in + ATP + H2O
-
Streptomyces rochei tetracyclin/out + ADP + phosphate
-
?
tetracyclin/in + ATP + H2O
-
Streptomyces rochei F20 tetracyclin/out + ADP + phosphate
-
?
tobramycin/in + ATP + H2O
-
Streptomyces rochei tobramycin/out + ADP + phosphate
-
?