Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 7.6.2.2 extracted from

  • Van Veen, H.W.; Konings, W.N.
    The ABC family of multidrug transporters in microorganisms (1998), Biochim. Biophys. Acta, 1365, 31-36.
    View publication on PubMed
Search for more literature for 7.6.2.2

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens overexpression of the multidrug resistance P-glycoprotein and the multidrug resistance-associated protein MRP1 is a principal cause of resistance of cancer to chemotherapy ?
-
 ?
additional information Entamoeba histolytica enzyme plays an important role in microbial resistance to neutral or positively charged amphiphilic drugs ?
-
 ?
additional information Leishmania donovani enzyme plays an important role in microbial resistance to neutral or positively charged amphiphilic drugs ?
-
 ?
additional information Candida albicans enzyme plays an important role in microbial resistance to neutral or positively charged amphiphilic drugs ?
-
 ?
additional information Plasmodium falciparum enzyme plays an important role in microbial resistance to neutral or positively charged amphiphilic drugs ?
-
 ?

Organism

Organism UniProt Comment Textmining
Bacillus subtilis
-
-
-
Caenorhabditis elegans
-
-
-
Candida albicans
-
-
-
Cricetulus griseus
-
 chinese hamster
-
Entamoeba histolytica
-
-
-
Escherichia coli
-
-
-
Haemophilus influenzae
-
-
-
Helicobacter pylori
-
-
-
Homo sapiens
-
-
-
Lactococcus lactis
-
-
-
Leishmania donovani
-
-
-
Leishmania tarentolae
-
-
-
Levilactobacillus brevis
-
-
-
Mycoplasma genitalium
-
-
-
Plasmodium falciparum
-
-
-
Saccharomyces cerevisiae
-
-
-
Staphylococcus aureus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
RPMI-8226 cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information overexpression of the multidrug resistance P-glycoprotein and the multidrug resistance-associated protein MRP1 is a principal cause of resistance of cancer to chemotherapy Homo sapiens ?
-
 ?
additional information enzyme plays an important role in microbial resistance to neutral or positively charged amphiphilic drugs Entamoeba histolytica ?
-
 ?
additional information enzyme plays an important role in microbial resistance to neutral or positively charged amphiphilic drugs Leishmania donovani ?
-
 ?
additional information enzyme plays an important role in microbial resistance to neutral or positively charged amphiphilic drugs Candida albicans ?
-
 ?
additional information enzyme plays an important role in microbial resistance to neutral or positively charged amphiphilic drugs Plasmodium falciparum ?
-
 ?