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Literature summary for 7.6.2.11 extracted from

  • Burnat, M.; Li, B.; Kim, S.; Michael, A.; Flores, E.
    Homospermidine biosynthesis in the cyanobacterium Anabaena requires a deoxyhypusine synthase homologue and is essential for normal diazotrophic growth (2018), Mol. Microbiol., 109, 763-780 .
    View publication on PubMed
Search for more literature for 7.6.2.11

Cloned(Commentary)

Cloned (Comment) Organism
gene cluster potADB, or genes all5044, all5043, and all5042, encoding a polyamine ABC transporter, DELTAall5044-all5042::C.S3 Nostoc sp. PCC 7120 = FACHB-418

Protein Variants

Protein Variants Comment Organism
additional information inactivation of the gene cluster potADB Nostoc sp. PCC 7120 = FACHB-418

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Nostoc sp. PCC 7120 = FACHB-418 16020
-

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ required Nostoc sp. PCC 7120 = FACHB-418

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O + polyamine-[polyamine-binding protein][side 1] Nostoc sp. PCC 7120 = FACHB-418
-
 ADP + phosphate + polyamine[side 2] + [polyamine-binding protein][side 1]
-
 ?
ATP + H2O + polyamine-[polyamine-binding protein][side 1] Nostoc sp. PCC 7120 = FACHB-418 UTEX 2576
-
 ADP + phosphate + polyamine[side 2] + [polyamine-binding protein][side 1]
-
 ?
ATP + H2O + polyamine-[polyamine-binding protein][side 1] Nostoc sp. PCC 7120 = FACHB-418 SAG 25.82
-
 ADP + phosphate + polyamine[side 2] + [polyamine-binding protein][side 1]
-
 ?

Organism

Organism UniProt Comment Textmining
Nostoc sp. PCC 7120 = FACHB-418 Q8YM92 AND Q8YM93 AND Q8YM94 genes all5044, all5043, and all5042, encoding spermidine/putrescine import ATP-binding protein PotA, polyamine-binding protein of polyamine ABC transporter PotD, and permease protein of polyamine ABC transporter PotB; i.e. Anabaena sp. PCC 7120
-
Nostoc sp. PCC 7120 = FACHB-418 SAG 25.82 Q8YM92 AND Q8YM93 AND Q8YM94 genes all5044, all5043, and all5042, encoding spermidine/putrescine import ATP-binding protein PotA, polyamine-binding protein of polyamine ABC transporter PotD, and permease protein of polyamine ABC transporter PotB; i.e. Anabaena sp. PCC 7120
-
Nostoc sp. PCC 7120 = FACHB-418 UTEX 2576 Q8YM92 AND Q8YM93 AND Q8YM94 genes all5044, all5043, and all5042, encoding spermidine/putrescine import ATP-binding protein PotA, polyamine-binding protein of polyamine ABC transporter PotD, and permease protein of polyamine ABC transporter PotB; i.e. Anabaena sp. PCC 7120
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + polyamine-[polyamine-binding protein][side 1]
-
 Nostoc sp. PCC 7120 = FACHB-418 ADP + phosphate + polyamine[side 2] + [polyamine-binding protein][side 1]
-
 ?
ATP + H2O + polyamine-[polyamine-binding protein][side 1]
-
 Nostoc sp. PCC 7120 = FACHB-418 UTEX 2576 ADP + phosphate + polyamine[side 2] + [polyamine-binding protein][side 1]
-
 ?
ATP + H2O + polyamine-[polyamine-binding protein][side 1]
-
 Nostoc sp. PCC 7120 = FACHB-418 SAG 25.82 ADP + phosphate + polyamine[side 2] + [polyamine-binding protein][side 1]
-
 ?
ATP + H2O + putrescine-[polyamine-binding protein][side 1]
-
 Nostoc sp. PCC 7120 = FACHB-418 ADP + phosphate + putrescine[side 2] + [polyamine-binding protein][side 1]
-
 ?
ATP + H2O + putrescine-[polyamine-binding protein][side 1]
-
 Nostoc sp. PCC 7120 = FACHB-418 UTEX 2576 ADP + phosphate + putrescine[side 2] + [polyamine-binding protein][side 1]
-
 ?
ATP + H2O + putrescine-[polyamine-binding protein][side 1]
-
 Nostoc sp. PCC 7120 = FACHB-418 SAG 25.82 ADP + phosphate + putrescine[side 2] + [polyamine-binding protein][side 1]
-
 ?
ATP + H2O + spermidine-[polyamine-binding protein][side 1]
-
 Nostoc sp. PCC 7120 = FACHB-418 ADP + phosphate + spermidine[side 2] + [polyamine-binding protein][side 1]
-
 ?
ATP + H2O + spermidine-[polyamine-binding protein][side 1]
-
 Nostoc sp. PCC 7120 = FACHB-418 UTEX 2576 ADP + phosphate + spermidine[side 2] + [polyamine-binding protein][side 1]
-
 ?
ATP + H2O + spermidine-[polyamine-binding protein][side 1]
-
 Nostoc sp. PCC 7120 = FACHB-418 SAG 25.82 ADP + phosphate + spermidine[side 2] + [polyamine-binding protein][side 1]
-
 ?

Synonyms

Synonyms Comment Organism
all5042
-
 Nostoc sp. PCC 7120 = FACHB-418
all5043
-
 Nostoc sp. PCC 7120 = FACHB-418
all5044
-
 Nostoc sp. PCC 7120 = FACHB-418
permease protein of polyamine ABC transporter
-
 Nostoc sp. PCC 7120 = FACHB-418
polyamine ABC transporter
-
 Nostoc sp. PCC 7120 = FACHB-418
polyamine-binding protein of polyamine ABC transporter
-
 Nostoc sp. PCC 7120 = FACHB-418
PotA
-
 Nostoc sp. PCC 7120 = FACHB-418
potADB
-
 Nostoc sp. PCC 7120 = FACHB-418
PotB
-
 Nostoc sp. PCC 7120 = FACHB-418
PotD
-
 Nostoc sp. PCC 7120 = FACHB-418
spermidine/putrescine import ATP-binding protein
-
 Nostoc sp. PCC 7120 = FACHB-418

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Nostoc sp. PCC 7120 = FACHB-418

General Information

General Information Comment Organism
malfunction inactivation of the gene cluster potADB, encoding a polyamine ABC transporter disrupted diazotrophic growth, corroborates the importance of polyamine homeostasis in Nostoc sp. PCC 7120 Nostoc sp. PCC 7120 = FACHB-418
additional information ABC uptake transporters typically comprise one periplasmic solute-binding protein (SBP), two integral membrane proteins (transmembrane domains [TMD]) and two nucleotide-binding domains (NBD) that hydrolyze ATP in the cytoplasm, in which the TMD and NBD may be homo- or heterodimers Nostoc sp. PCC 7120 = FACHB-418