Protein Variants | Comment | Organism |
---|---|---|
F79A | the mutation causes a considerable reduction in enzyme activity | Leishmania sp. |
N58A | the mutation causes a considerable reduction in enzyme activity | Leishmania sp. |
Y65A | the mutation causes a considerable reduction in enzyme activity | Leishmania sp. |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
plasma membrane | - |
Leishmania sp. | 5886 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Leishmania sp. | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O + miltefosine[side 1] | - |
Leishmania sp. | ADP + phosphate + miltefosine[side 2] | - |
? | |
ATP + H2O + phosphatidylcholine[side 1] | - |
Leishmania sp. | ADP + phosphate + phosphatidylcholine[side 2] | - |
? | |
ATP + H2O + phosphatidylethanolamine[side 1] | - |
Leishmania sp. | ADP + phosphate + phosphatidylethanolamine[side 2] | - |
? |
Synonyms | Comment | Organism |
---|---|---|
LMT translocase | - |
Leishmania sp. |
miltefosine transporter | - |
Leishmania sp. |
P4-ATPase | - |
Leishmania sp. |