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Literature summary for 7.6.2.1 extracted from

  • Takagi, K.; Iwamoto, K.; Kobayashi, S.; Horiuchi, H.; Fukuda, R.; Ohta, A.
    Involvement of Golgi-associated retrograde protein complex in the recycling of the putative Dnf aminophospholipid flippases in yeast (2012), Biochem. Biophys. Res. Commun., 417, 490-494.
    View publication on PubMed
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Cloned(Commentary)

Cloned (Comment) Organism
genes DNF1 and DNF2, expression of EGFP-tagged Dnf1p and Dnf2p in Saccharomyces cerevisiae deletion mutant strains vps51DELTA, vps52DELTA, vps53DELTA, and vps54DELTA Saccharomyces cerevisiae

Localization

Localization Comment Organism GeneOntology No. Textmining
plasma membrane
-
 Saccharomyces cerevisiae 5886
-

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
 genes DNF1 and DNF2
-

Synonyms

Synonyms Comment Organism
aminophospholipid flippase
-
 Saccharomyces cerevisiae
Dnf1p
-
 Saccharomyces cerevisiae
Dnf2p
-
 Saccharomyces cerevisiae
inward-directed phospholipid translocase
-
 Saccharomyces cerevisiae
phospholipid flippase
-
 Saccharomyces cerevisiae
phospholipid translocase
-
 Saccharomyces cerevisiae

General Information

General Information Comment Organism
malfunction mutants defective in genes VPS51, VPS52, VPS53, and VPS54, encoding the Golgi-associated retrograde protein (GARP) complex, the Rab family small GTPase Ypt6p, its guanine nucleotide exchange factor proteins, or Tlg2p t-SNARE, show abberrant intracellular localization of Dnf1p and Dnf2p Saccharomyces cerevisiae
physiological function Dnf2p is the putative inward-directed phospholipid translocase, i.e. flippase, of the plasma membrane Saccharomyces cerevisiae