Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
plasma membrane | - |
Saccharomyces cerevisiae | 5886 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O + phospholipid/in | Saccharomyces cerevisiae | Dnf1p and Dnf2p are necessary for the internalization phospholipids across the plasma membrane of Saccharomyces cerevisiae, overview. ATP hydrolysis is not sufficient for phospholipid flip in the absence of the proton electrochemical gradient across the plasma membrane, the proton electrochemical gradient is required for phospholipid flip across the plasma membrane of yeast | ADP + phosphate + phospholipid/out | - |
? | |
ATP + H2O + phospholipid/in | Saccharomyces cerevisiae LMY65 | Dnf1p and Dnf2p are necessary for the internalization phospholipids across the plasma membrane of Saccharomyces cerevisiae, overview. ATP hydrolysis is not sufficient for phospholipid flip in the absence of the proton electrochemical gradient across the plasma membrane, the proton electrochemical gradient is required for phospholipid flip across the plasma membrane of yeast | ADP + phosphate + phospholipid/out | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Saccharomyces cerevisiae | - |
and strains LMY67, LMY69, and LMY94 | - |
Saccharomyces cerevisiae LMY65 | - |
and strains LMY67, LMY69, and LMY94 | - |
Source Tissue | Comment | Organism | Textmining |
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Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O + phospholipid/in | Dnf1p and Dnf2p are necessary for the internalization phospholipids across the plasma membrane of Saccharomyces cerevisiae, overview. ATP hydrolysis is not sufficient for phospholipid flip in the absence of the proton electrochemical gradient across the plasma membrane, the proton electrochemical gradient is required for phospholipid flip across the plasma membrane of yeast | Saccharomyces cerevisiae | ADP + phosphate + phospholipid/out | - |
? | |
ATP + H2O + phospholipid/in | ATP-dependent transport of phospholipids from outer to the inner monolayer of the cell membrane to maintain lipid asymmetry, usage of fluorescent labeled 7-nitrobenz-2-oxa-1,3-diazol-4-yl-labeled, NBD-labeled, phospholipid substrate. ATP hydrolysis is not sufficient for phospholipid flip in the absence of the proton electrochemical gradient across the plasma membrane, the proton electrochemical gradient is required for phospholipid flip across the plasma membrane of yeast | Saccharomyces cerevisiae | ADP + phosphate + phospholipid/out | - |
? | |
ATP + H2O + phospholipid/in | Dnf1p and Dnf2p are necessary for the internalization phospholipids across the plasma membrane of Saccharomyces cerevisiae, overview. ATP hydrolysis is not sufficient for phospholipid flip in the absence of the proton electrochemical gradient across the plasma membrane, the proton electrochemical gradient is required for phospholipid flip across the plasma membrane of yeast | Saccharomyces cerevisiae LMY65 | ADP + phosphate + phospholipid/out | - |
? | |
ATP + H2O + phospholipid/in | ATP-dependent transport of phospholipids from outer to the inner monolayer of the cell membrane to maintain lipid asymmetry, usage of fluorescent labeled 7-nitrobenz-2-oxa-1,3-diazol-4-yl-labeled, NBD-labeled, phospholipid substrate. ATP hydrolysis is not sufficient for phospholipid flip in the absence of the proton electrochemical gradient across the plasma membrane, the proton electrochemical gradient is required for phospholipid flip across the plasma membrane of yeast | Saccharomyces cerevisiae LMY65 | ADP + phosphate + phospholipid/out | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Dnf1p and Dnf2p | - |
Saccharomyces cerevisiae |
More | the enzymes belong to the the P4 family of P-type ATPases | Saccharomyces cerevisiae |