Protein Variants | Comment | Organism |
---|---|---|
additional information | lem3 mutants are not affected in Lem3p-Dnf1p complex formation, but show a synthetic growth defect with the null mutation CDC50, overview | Saccharomyces cerevisiae |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
endosome | Cdc50p-Drs2p complex | Saccharomyces cerevisiae | 5768 | - |
Golgi membrane | Cdc50p-Drs2p complex | Saccharomyces cerevisiae | 139 | - |
plasma membrane | Lem3p-Dnf1p complex | Saccharomyces cerevisiae | 5886 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | - |
Saccharomyces cerevisiae |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Saccharomyces cerevisiae | the Lem3p-Dnf1p complex can substitute for the Cdc50p-Drs2p complex, its redundant partner in the endosomal/trans-Golgi network compartments | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Saccharomyces cerevisiae | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O + 1-palmitoyl-2-(6-(7-nitro-2-1,3-benzoxadiazole)-aminocaproyl)-phosphatidylcholine/out | internalization through the plasma membrane by the Dnf1p-Lem3p complex | Saccharomyces cerevisiae | ADP + phosphate + 1-palmitoyl-2-(6-(7-nitro-2-1,3-benzoxadiazole)-aminocaproyl)-phosphatidylcholine/in | - |
? | |
ATP + H2O + 1-palmitoyl-2-(6-(7-nitro-2-1,3-benzoxadiazole)-aminocaproyl)-phosphatidylethanolamine/out | internalization through the plasma membrane by the Dnf1p-Lem3p complex | Saccharomyces cerevisiae | ADP + phosphate + 1-palmitoyl-2-(6-(7-nitro-2-1,3-benzoxadiazole)-aminocaproyl)-phosphatidylethanolamine/in | - |
? | |
additional information | the Lem3p-Dnf1p complex can substitute for the Cdc50p-Drs2p complex, its redundant partner in the endosomal/trans-Golgi network compartments | Saccharomyces cerevisiae | ? | - |
? | |
additional information | Dnf1p forms a complex with Lem3p acting as aminophospholipid translocase | Saccharomyces cerevisiae | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
aminophospholipid translocase | - |
Saccharomyces cerevisiae |
APLT | - |
Saccharomyces cerevisiae |
Cdc50p-Drs2p | - |
Saccharomyces cerevisiae |
Dnf1p | - |
Saccharomyces cerevisiae |
Dnf1p-Lem3p | - |
Saccharomyces cerevisiae |
Drs2p | - |
Saccharomyces cerevisiae |
More | the enzyme belongs to the P-type ATPases | Saccharomyces cerevisiae |
phospholipid-translocase | - |
Saccharomyces cerevisiae |