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Literature summary for 7.6.2.1 extracted from

  • Devaux, P.F.; Zachowski, A.; Morrot, G.; Cribier, S.; Fellmann, P.; Geldwerth, D.; Bitbol, M.; Herve, P.
    Control of the transmembrane phospholipid distribution in eukaryotic cells by aminophospholipid translocase (1990), Biotechnol. Appl. Biochem., 12, 517-522.
    View publication on PubMed
Search for more literature for 7.6.2.1

Inhibitors

Inhibitors Comment Organism Structure
NEM
-
 Homo sapiens
vanadate
-
 Bos taurus
vanadate
-
 Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
chromaffin granule
-
 Bos taurus 42583
-
endoplasmic reticulum
-
 Rattus norvegicus 5783
-
plasma membrane plasma membrane Homo sapiens 5886
-

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ required Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O Cavia porcellus selectively pumps the aminophospholipids phospatidylserine and phosphatidylethanolamine from the outer to the inner monolayer of eukaryotic cells and is predominantly responsible for the asymmetric phospholipid distribution of the plasma membrane ADP + phosphate
-
 ?
ATP + H2O Homo sapiens selectively pumps the aminophospholipids phospatidylserine and phosphatidylethanolamine from the outer to the inner monolayer of eukaryotic cells and is predominantly responsible for the asymmetric phospholipid distribution of the plasma membrane ADP + phosphate
-
 ?
ATP + H2O Rattus norvegicus selectively pumps the aminophospholipids phospatidylserine and phosphatidylethanolamine from the outer to the inner monolayer of eukaryotic cells and is predominantly responsible for the asymmetric phospholipid distribution of the plasma membrane ADP + phosphate
-
 ?
ATP + H2O Sus scrofa selectively pumps the aminophospholipids phospatidylserine and phosphatidylethanolamine from the outer to the inner monolayer of eukaryotic cells and is predominantly responsible for the asymmetric phospholipid distribution of the plasma membrane ADP + phosphate
-
 ?
ATP + H2O Bos taurus selectively pumps the aminophospholipids phospatidylserine and phosphatidylethanolamine from the outer to the inner monolayer of eukaryotic cells and is predominantly responsible for the asymmetric phospholipid distribution of the plasma membrane ADP + phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-
Cavia porcellus
-
-
-
Homo sapiens
-
-
-
Rattus norvegicus
-
-
-
Sus scrofa
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
erythrocyte
-
 Homo sapiens
-
liver
-
 Bos taurus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O
-
 Cavia porcellus ADP + phosphate
-
 ?
ATP + H2O
-
 Rattus norvegicus ADP + phosphate
-
 ?
ATP + H2O
-
 Sus scrofa ADP + phosphate
-
 ?
ATP + H2O
-
 Bos taurus ADP + phosphate
-
 ?
ATP + H2O selectively pumps the aminophospholipids phospatidylserine and phosphatidylethanolamine from the outer to the inner monolayer of eukaryotic cells and is predominantly responsible for the asymmetric phospholipid distribution of the plasma membrane Cavia porcellus ADP + phosphate
-
 ?
ATP + H2O selectively pumps the aminophospholipids phospatidylserine and phosphatidylethanolamine from the outer to the inner monolayer of eukaryotic cells and is predominantly responsible for the asymmetric phospholipid distribution of the plasma membrane Homo sapiens ADP + phosphate
-
 ?
ATP + H2O selectively pumps the aminophospholipids phospatidylserine and phosphatidylethanolamine from the outer to the inner monolayer of eukaryotic cells and is predominantly responsible for the asymmetric phospholipid distribution of the plasma membrane Rattus norvegicus ADP + phosphate
-
 ?
ATP + H2O selectively pumps the aminophospholipids phospatidylserine and phosphatidylethanolamine from the outer to the inner monolayer of eukaryotic cells and is predominantly responsible for the asymmetric phospholipid distribution of the plasma membrane Sus scrofa ADP + phosphate
-
 ?
ATP + H2O selectively pumps the aminophospholipids phospatidylserine and phosphatidylethanolamine from the outer to the inner monolayer of eukaryotic cells and is predominantly responsible for the asymmetric phospholipid distribution of the plasma membrane Bos taurus ADP + phosphate
-
 ?
ATP + H2O ATPase activity is stimulated by phosphatidylserine but not by phosphatidylcholine Homo sapiens ADP + phosphate
-
 ?