Cloned (Comment) | Organism |
---|---|
wild-type nucleotide-binding domains GlcV and the E166A and G144A mutant are expressed in Escherichia coli | Saccharolobus solfataricus |
Protein Variants | Comment | Organism |
---|---|---|
E166A | the wild-type enzyme has a conserved domain structure with two membrane-spanning domains that form the transport channel and two cytosolic nucleotide-binding domains that energize the transport reaction. Binding of ATP to the nucleotide-binding domain monomer results in formation of a nucleotide-binding domain dimer. Hydrolysis of the ATP drives the dissociation of the dimer. The mutant enzymed is defective in dimer dissociation | Saccharolobus solfataricus |
G144A | | the wild-type enzyme has a conserved domain structure with two membrane-spanning domains that form the transport channel and two cytosolic nucleotide-binding domains that energize the transport reaction. Binding of ATP to the nucleotide-binding domain monomer results in formation of a nucleotide-binding domain dimer. Hydrolysis of the ATP drives the dissociation of the dimer. The mutant enzyme is unable to dimerize | Saccharolobus solfataricus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Saccharolobus solfataricus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Saccharolobus solfataricus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O + D-glucose/out | - |
Saccharolobus solfataricus | ADP + phosphate + D-glucose/in | - |
? |
Synonyms | Comment | Organism |
---|---|---|
glucose ABC transporter | - |
Saccharolobus solfataricus |