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Literature summary for 7.5.2.5 extracted from

  • Suits, M.D.; Sperandeo, P.; Deho, G.; Polissi, A.; Jia, Z.
    Novel structure of the conserved gram-negative lipopolysaccharide transport protein A and mutagenesis analysis (2008), J. Mol. Biol., 380, 476-488.
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining
inner membrane
-
Escherichia coli
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O + Lipid A/in Escherichia coli translocation of the lipid A core moiety across the inner membrane requires the ABC transporter MsbA,which mediates the flipping from the inner leaflet to the outer leaflet of the inner membrane, lipopolysaccharide translocation mechanism and system, structure modelling, overview ADP + phosphate + Lipid A/out
-
?

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
gene msbA
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + Lipid A/in
-
Escherichia coli ADP + phosphate + Lipid A/out
-
?
ATP + H2O + Lipid A/in translocation of the lipid A core moiety across the inner membrane requires the ABC transporter MsbA,which mediates the flipping from the inner leaflet to the outer leaflet of the inner membrane, lipopolysaccharide translocation mechanism and system, structure modelling, overview Escherichia coli ADP + phosphate + Lipid A/out
-
?

Synonyms

Synonyms Comment Organism
MsbA
-
Escherichia coli

Cofactor

Cofactor Comment Organism Structure
ATP
-
Escherichia coli