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Literature summary for 7.5.2.1 extracted from
- Substrate transport activation is mediated through second periplasmic loop of transmembrane protein MalF in maltose transport complex of Escherichia coli (2012), J. Biol. Chem., 287, 17040-17049.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| MalF | MalF stimulates the substrate transport activity through its second periplasmic loop, overview | Escherichia coli |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + H2O + maltose/out | Escherichia coli | - |
ADP + phosphate + maltose/in | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | - |
gene malF | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + H2O + maltose/out | - |
Escherichia coli | ADP + phosphate + maltose/in | - |
? | |
| ATP + H2O + maltose/out | the transmembrane protein MalF, MalF-P2, of the maltose ATP-binding cassette transporter MalFGK2-E as an important element in the recognition of substrate by the maltose-binding protein MalE. MalF-P2 is not only responsible for substrate recognition, but also directly involved in activation of substrate transport. Substrate transport model for MalFGK2-E, isothermal titration calorimetry and molecular dynamics simulation, overview | Escherichia coli | ADP + phosphate + maltose/in | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| MalF | - |
Escherichia coli |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 25 | - |
assay at | Escherichia coli |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.4 | - |
assay at | Escherichia coli |
General Information
| General Information | Comment | Organism |
|---|---|---|
| additional information | substrate transport model for MalFGK2 | Escherichia coli |
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