Literature summary for 7.4.2.5 extracted from

Negom Kouodom, M.; Ronconi, L.; Celegato, M.; Nardon, C.; Marchiò, L.; Dou, Q.; Aldinucci, D.; Formaggio, F.; Fregona, D.
Toward the selective delivery of chemotherapeutics into tumor cells by targeting peptide transporters: Tailored gold-based anticancer peptidomimetics (2012), J. Med. Chem., 55, 2212-2226.

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Inhibitors

Inhibitors	Comment	Organism	Structure
cisplatin	IC50 value for growth inhibition of cell line PC-3 0.0033 mM, DU-145 0.0045 mM, 2008 0.0194 mM, C-13 0.117 mM, L-540 0.0025 mM	Homo sapiens
[AuIIIBr2(dtc-Sar-Aib-O(t-Bu))]	IC50 value for growth inhibition of cell line PC-3 0.0008 mM, DU-145 0.0014 mM, 2008 0.0045 mM, C-13 0.0037 mM, L-540 0.0015 mM	Homo sapiens
[AuIIICl2(dtc-Sar-Aib-O(t-Bu))]	IC50 value for growth inhibition of cell line PC-3 0.0011 mM, DU-145 0.0022 mM, 2008 0.0047 mM, C-13 0.0051 mM, L-540 0.0017 mM	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
DU-145 cell	-	Homo sapiens	-
L-540 cell	-	Homo sapiens	-
OV2008/C13 cell	cisplatin resistant cell	Homo sapiens	-
PC-3 cell	-	Homo sapiens	-

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Release 2023.1 (January 2023)