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BRENDA support

Literature summary for 7.4.2.5 extracted from

  • Wu, Z.C.; de Keyzer, J.; Kedrov, A.; Driessen, A.J.
    Competitive binding of the SecA ATPase and ribosomes to the SecYEG translocon (2012), J. Biol. Chem., 287, 7885-7895.
    View publication on PubMedView publication on EuropePMC

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
Escherichia coli 16020
-

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-
Escherichia coli SF100
-
-
-

General Information

General Information Comment Organism
physiological function Both SecA and the ribosome need to interact with the translocon during membrane protein insertion. SecA and ribosome binding to the translocon is mutually exclusive, implying that during membrane protein insertion, both ligands bind the translocon in a sequential manner Escherichia coli