Any feedback?
Literature summary for 7.4.2.5 extracted from
- Priming of protective anti-Listeria monocytogenes memory CD8+ T cells requires a functional SecA2 secretion system (2011), Infect. Immun., 79, 2396-2403.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Listeria monocytogenes | - |
- |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| SecA2 | - |
Listeria monocytogenes |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | Similarly to a SecA2 deletion mutant, a SecA2 ATPase bearing a mutated nucleotide binding site exhibits rough colonies, a bacterial chaining phenotype, an impaired protein secretion profile, and in vivo virulence in comparison to wild-type Listeria monocytogenes. Mice immunized with the SecA2 nucelotide binding site mutant are not protected against secondary infection with wild-type Listeria monocytogenes and do not develop CCL3+ memory CD8+ T cells | Listeria monocytogenes |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
