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Literature summary for 7.4.2.5 extracted from
- Protein and peptide secretion by ABC exporters (1998), Res. Microbiol., 149, 163-170.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| membrane | TAP1 and TAP2, hydrophobic N-terminus, C-terminal ABC domain | Homo sapiens | 16020 | - |
| membrane | TAP1 and TAP2, hydrophobic N-terminus, C-terminal ABC domain | Rattus norvegicus | 16020 | - |
| membrane | TAP1 and TAP2, hydrophobic N-terminus, C-terminal ABC domain | Mus sp. | 16020 | - |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + H2O + alpha-haemolysin/in | Escherichia coli | - |
ADP + phosphate + alpha-haemolysin/out | - |
? |  |
| ATP + H2O + alpha-haemolysin/in | Enterococcus faecalis | - |
ADP + phosphate + alpha-haemolysin/out | - |
? | |
| ATP + H2O + protein/in | Gram-negative bacteria | - |
ADP + phosphate + protein/out | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Enterococcus faecalis | - |
- |
- |
| Escherichia coli | - |
- |
- |
| Gram-negative bacteria | - |
- |
- |
| Homo sapiens | - |
- |
- |
| Mus sp. | - |
- |
- |
| Rattus norvegicus | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + H2O + alpha-haemolysin/in | - |
Escherichia coli | ADP + phosphate + alpha-haemolysin/out | - |
? | |
| ATP + H2O + alpha-haemolysin/in | - |
Enterococcus faecalis | ADP + phosphate + alpha-haemolysin/out | - |
? | |
| ATP + H2O + protein/in | - |
Gram-negative bacteria | ADP + phosphate + protein/out | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| More | ABC transporter | Escherichia coli |
| More | ABC transporter | Gram-negative bacteria |
| More | components involved are two helper proteins and the ABC protein: membrane fusion protein (MFP), outer membrane protein (OMP), and the ABC protein | Escherichia coli |
| More | components involved are two helper proteins and the ABC protein: membrane fusion protein (MFP), outer membrane protein (OMP), and the ABC protein | Gram-negative bacteria |
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Release 2023.1 (January 2023)
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