Literature summary for 7.4.2.3 extracted from

Yanoma, T.; Ogata, K.; Yokobori, T.; Ide, M.; Mochiki, E.; Toyomasu, Y.; Yanai, M.; Kogure, N.; Kimura, A.; Suzuki, M.; Nakazawa, N.; Bai, T.; Oyama, T.; Asao, T.; Shirabe, K.; Kuwano, H.
Heat shock-induced HIKESHI protects cell viability via nuclear translocation of heat shock protein 70 (2017), Oncol. Rep., 38, 1500-1506 .

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Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
nucleus	-	Homo sapiens	5634	-

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
ATP + H2O + heat shock protein 70[side 1]	Homo sapiens	-	ADP + phosphate + heat shock protein 70[side 2]	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
gastric cancer cell	-	Homo sapiens	-
KATO-III cell	-	Homo sapiens	-
MKN-45 cell	-	Homo sapiens	-
MKN-7 cell	-	Homo sapiens	-
MKN-74 cell	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + H2O + heat shock protein 70[side 1]	-	Homo sapiens	ADP + phosphate + heat shock protein 70[side 2]	-	?

Synonyms

Synonyms	Comment	Organism
HIKESHI	-	Homo sapiens

General Information

General Information	Comment	Organism
physiological function	the protein transports heat shock protein 70 into the nucleus to protect cellular homeostasis against heat shock	Homo sapiens

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Release 2023.1 (January 2023)