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Literature summary for 7.4.2.3 extracted from
- ATP hydrolysis is essential for Bag-1M-mediated inhibition of the DNA binding by the glucocorticoid receptor (2009), Biochem. Biophys. Res. Commun., 390, 77-81.
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Chlorocebus aethiops | - |
African green monkey | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| COS-7 cell | - |
Chlorocebus aethiops | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + H2O | ATP hydrolysis needed by Bcl-2 associated athanogene 1M (Bag-1M), which interacts with the ATPase domain of Hsp70 to modulate the release of the substrate from Hsp70. ATP hydrolysis enhances Bag-1M-mediated inhibition of the DNA binding by the glucocorticoid receptor GR | Chlorocebus aethiops | ADP + phosphate | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Hsp70 | - |
Chlorocebus aethiops |
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Release 2023.1 (January 2023)
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