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Literature summary for 7.4.2.1 extracted from

  • Price, D.R.; Wilson, A.C.; Luetje, C.W.
    Proton-dependent glutamine uptake by aphid bacteriocyte amino acid transporter ApGLNT1 (2015), Biochim. Biophys. Acta, 1848, 2085-2091 .
    View publication on PubMed
Search for more literature for 7.4.2.1

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Xenopus laevis oocytes Acyrthosiphon pisum

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
5.4
-
 L-glutamine-[L-glutamine-binding protein][side 1] at pH 6.0 and 25°C Acyrthosiphon pisum

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Acyrthosiphon pisum 16020
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O + L-glutamine-[L-glutamine-binding protein][side 1] Acyrthosiphon pisum the enzyme is specific for glutamine ADP + phosphate + L-glutamine[side 2] + [L-glutamine-binding protein][side 1]
-
 ?

Organism

Organism UniProt Comment Textmining
Acyrthosiphon pisum F8RL01
-
-

Source Tissue

Source Tissue Comment Organism Textmining
bacteriocyte
-
 Acyrthosiphon pisum
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + L-glutamine-[L-glutamine-binding protein][side 1] the enzyme is specific for glutamine Acyrthosiphon pisum ADP + phosphate + L-glutamine[side 2] + [L-glutamine-binding protein][side 1]
-
 ?

Synonyms

Synonyms Comment Organism
ACYPI001018
-
 Acyrthosiphon pisum
GLNT1
-
 Acyrthosiphon pisum
glutamine transporter 1
-
 Acyrthosiphon pisum

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
5
-
 maximum glutamine uptake occurs at extracellular pH 5.0, and is significantly reduced as extracellular pH increases to pH 8.0 Acyrthosiphon pisum

General Information

General Information Comment Organism
physiological function the enzyme generates inward glutamine-dependent currents and regulates glutamine import into bacteriocytes Acyrthosiphon pisum