Literature summary for 7.4.2.1 extracted from

Huseinovic, A.; Dekker, S.J.; Boogaard, B.; Vermeulen, N.P.E.; Kooter, J.M.; Vos, J.C.
Acetaminophen reduces the protein levels of high affinity amino acid permeases and causes tryptophan depletion (2018), Amino Acids, 50, 1377-1390 .

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General Stability

General Stability	Organism
acetaminophen causes degradation of the enzyme	Saccharomyces cerevisiae

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
ATP + H2O + L-histidine-[L-histidine-binding protein][side 1]	Saccharomyces cerevisiae	-	ADP + phosphate + L-histidine[side 2] + [L-histidine-binding protein][side 1]	-	?
ATP + H2O + L-histidine-[L-histidine-binding protein][side 1]	Saccharomyces cerevisiae BY4741	-	ADP + phosphate + L-histidine[side 2] + [L-histidine-binding protein][side 1]	-	?

Organism

Organism	UniProt	Comment	Textmining
Saccharomyces cerevisiae	-	-	-
Saccharomyces cerevisiae BY4741	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + H2O + L-histidine-[L-histidine-binding protein][side 1]	-	Saccharomyces cerevisiae	ADP + phosphate + L-histidine[side 2] + [L-histidine-binding protein][side 1]	-	?
ATP + H2O + L-histidine-[L-histidine-binding protein][side 1]	-	Saccharomyces cerevisiae BY4741	ADP + phosphate + L-histidine[side 2] + [L-histidine-binding protein][side 1]	-	?

Synonyms

Synonyms	Comment	Organism
AAP	-	Saccharomyces cerevisiae
amino acid permease	-	Saccharomyces cerevisiae
Hip1	-	Saccharomyces cerevisiae

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Release 2023.1 (January 2023)