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Literature summary for 7.3.2.7 extracted from

  • Silver, S.
    Bacterial resistance to toxic metal ions - a review (1996), Gene, 179, 9-19.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
the arsenical resistance operon from IncN plasmid R46 contains the five genes ArsR, arsD, arsA, arsB and arsC. The chromosomal ars operon contains only arsB, arsC, and arsR Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O + arsenite/in Staphylococcus aureus the ars operon confers resistance to arsenite, arsenate and antimonite ADP + phosphate + arsenite/out
-
?
ATP + H2O + arsenite/in Escherichia coli the ars operon confers resistance to arsenite, arsenate and antimonite ADP + phosphate + arsenite/out
-
?
ATP + H2O + arsenite/in Staphylococcus carnosus the ars operon confers resistance to arsenite, arsenate and antimonite ADP + phosphate + arsenite/out
-
?

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
from IncN plasmid R46
-
Escherichia coli
-
from plasmid R773
-
Staphylococcus aureus
-
-
-
Staphylococcus carnosus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + arsenite/in
-
Staphylococcus aureus ADP + phosphate + arsenite/out
-
?
ATP + H2O + arsenite/in
-
Escherichia coli ADP + phosphate + arsenite/out
-
?
ATP + H2O + arsenite/in
-
Staphylococcus carnosus ADP + phosphate + arsenite/out
-
?
ATP + H2O + arsenite/in the ars operon confers resistance to arsenite, arsenate and antimonite Staphylococcus aureus ADP + phosphate + arsenite/out
-
?
ATP + H2O + arsenite/in the ars operon confers resistance to arsenite, arsenate and antimonite Escherichia coli ADP + phosphate + arsenite/out
-
?
ATP + H2O + arsenite/in the ars operon confers resistance to arsenite, arsenate and antimonite Staphylococcus carnosus ADP + phosphate + arsenite/out
-
?