Literature summary for 7.3.2.5 extracted from

Baxter, I.; Muthukumar, B.; Park, H.C.; Buchner, P.; Lahner, B.; Danku, J.; Zhao, K.; Lee, J.; Hawkesford, M.J.; Guerinot, M.L.; Salt, D.E.
Variation in molybdenum content across broadly distributed populations of Arabidopsis thaliana is controlled by a mitochondrial molybdenum transporter (MOT1) (2008), PLoS Genet., 4, e1000004.

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Cloned(Commentary)

Cloned (Comment)	Organism
genotyping, expression in protoplast mitochondrial membranes as GFP-tagged protein, quantitative expression analysis by realtime PCR, expression of MOT1 specifically enhances molybdenum accumulation in Saccharomyces cerevisiae by 5fold	Arabidopsis thaliana

Protein Variants

Protein Variants	Comment	Organism
additional information	a naturally occuring deletion mutation in the MOT1 promoter, leading to the mutants Ler-0 and Van-0, is strongly associated with low shoot molybdenum, occurring in seven of the accessions with the lowest shoot content of molybdenum. Consistent with the low molybdenum phenotype, MOT1 expression in low molybednum accessions is reduced, phenotype, overview	Arabidopsis thaliana

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
mitochondrial membrane	MOT1 contains an N-terminal mitochondrial targeting sequence	Arabidopsis thaliana	31966	-

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
ATP + H2O + molybdate/out	Arabidopsis thaliana	-	ADP + phosphate + molybdate/in	-	?

Organism

Organism	UniProt	Comment	Textmining
Arabidopsis thaliana	-	cv. Col-0	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
hypocotyl	-	Arabidopsis thaliana	-
leaf	-	Arabidopsis thaliana	-
root	high expression level, expression in the protodermal cells behind the root tip, and in epidermis and cortex at the elongation zone	Arabidopsis thaliana	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + H2O + molybdate/out	-	Arabidopsis thaliana	ADP + phosphate + molybdate/in	-	?

Synonyms

Synonyms	Comment	Organism
mitochondrial molybdenum transporter	-	Arabidopsis thaliana
molybdenum tansporter 1	-	Arabidopsis thaliana
More	the enzyme belongs to the sulfate transporter superfamily of enzyme	Arabidopsis thaliana
MOT1	-	Arabidopsis thaliana

Cofactor

Cofactor	Comment	Organism	Structure
ATP	-	Arabidopsis thaliana

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Release 2023.1 (January 2023)