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Literature summary for 7.2.4.5 extracted from

  • Buckel, W.; Semmler, R.
    A biotin-dependent sodium pump glutaconyl-CoA decarboxylase from Acidaminococcus fermentans (1982), FEBS Lett., 148, 35-38 .
    View publication on PubMed
Search for more literature for 7.2.4.5

Inhibitors

Inhibitors Comment Organism Structure
Avidin
-
 Acidaminococcus fermentans

Metals/Ions

Metals/Ions Comment Organism Structure
Na+ required Acidaminococcus fermentans

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
glutaconyal-CoA + Na+[side 1] Acidaminococcus fermentans
-
 crotonyl-CoA + CO2 + Na+[side 2]
-
 ?

Organism

Organism UniProt Comment Textmining
Acidaminococcus fermentans
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
glutaconyal-CoA + Na+[side 1]
-
 Acidaminococcus fermentans crotonyl-CoA + CO2 + Na+[side 2]
-
 ?

General Information

General Information Comment Organism
physiological function decarboxylation of glutaconyl-CoA to crotonyl-CoA is catalysed by a membrane-bound, biotin-dependent enzyme which requires Na+ for activity. The enzyme is able to convert the free energy of decarboxylation into a Na+ gradient Acidaminococcus fermentans