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Literature summary for 7.2.4.5 extracted from

  • Wohlfarth, G.; Buckel, P.; Buckel, W.
    On the structure and function of glutaconyl-CoA, a biotin dependent sodium pump from anaerobic bacteria (1986), Prog. Biotechnol., 2, 111-116.
No PubMed abstract available
Search for more literature for 7.2.4.5

Activating Compound

Activating Compound Comment Organism Structure
biotin biotinyl enzyme Peptoniphilus asaccharolyticus
biotin biotinyl enzyme Acidaminococcus fermentans

Cloned(Commentary)

Cloned (Comment) Organism
-
 Acidaminococcus fermentans

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Peptoniphilus asaccharolyticus 16020
-
membrane
-
 Acidaminococcus fermentans 16020
-

Metals/Ions

Metals/Ions Comment Organism Structure
Na+ required Peptoniphilus asaccharolyticus
Na+ required Acidaminococcus fermentans

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
30000
-
 x * 120000, alpha, biotin carrier + x * 60000, beta, transferase + x * 30000, gamma, sodium-dependent carboxybiotin decarboxylase, SDS-PAGE Acidaminococcus fermentans
60000
-
 x * 120000, alpha, biotin carrier + x * 60000, beta, transferase + x * 30000, gamma, sodium-dependent carboxybiotin decarboxylase, SDS-PAGE Acidaminococcus fermentans
120000
-
 x * 120000, alpha, biotin carrier + x * 60000, beta, transferase + x * 30000, gamma, sodium-dependent carboxybiotin decarboxylase, SDS-PAGE Acidaminococcus fermentans

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
glutaconyl-CoA + Na+[side 1] Peptoniphilus asaccharolyticus
-
 but-2-enoyl-CoA + CO2 + Na+[side 2]
-
 ?
glutaconyl-CoA + Na+[side 1] Acidaminococcus fermentans
-
 but-2-enoyl-CoA + CO2 + Na+[side 2]
-
 ?

Organism

Organism UniProt Comment Textmining
Acidaminococcus fermentans
-
 ATCC 25085
-
Peptoniphilus asaccharolyticus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4-carboxybut-2-enoyl-CoA + Na+[side 1]
-
 Peptoniphilus asaccharolyticus but-2-enoyl-CoA + CO2 + Na+[side 2]
-
 ?
4-carboxybut-2-enoyl-CoA + Na+[side 1]
-
 Acidaminococcus fermentans but-2-enoyl-CoA + CO2 + Na+[side 2]
-
 ?
glutaconyl-CoA + Na+[side 1]
-
 Peptoniphilus asaccharolyticus but-2-enoyl-CoA + CO2 + Na+[side 2]
-
 ?
glutaconyl-CoA + Na+[side 1]
-
 Acidaminococcus fermentans but-2-enoyl-CoA + CO2 + Na+[side 2]
-
 ?

Subunits

Subunits Comment Organism
? x * 120000, alpha, biotin carrier + x * 60000, beta, transferase + x * 30000, gamma, sodium-dependent carboxybiotin decarboxylase, SDS-PAGE Acidaminococcus fermentans

Cofactor

Cofactor Comment Organism Structure
biotin biotinyl enzyme Peptoniphilus asaccharolyticus
biotin biotinyl enzyme Acidaminococcus fermentans